Racemization processes at a quaternary carbon center in the context of the asymmetric Michael reaction

被引：17
|
作者：
Tan, K
Alvarez, R
Nour, M
Cavé, C
Chiaroni, A
Riche, C
d'Angelo, J
机构：
[1] Ctr Etud Pharmaceut, F-92296 Chatenay Malabry, France
[2] ICSN, CNRS, F-91198 Gif Sur Yvette, France
[3] UFR Pharm, Unite Mol Interet Biol, F-21079 Dijon, France
[4] Univ Vigo, Dept Quim Organ, Vigo 36200, Spain
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 30期
关键词：
asymmetric synthesis; Michael reaction; quaternary carbon center; racemization; X-ray crystallography;
D O I：
10.1016/S0040-4039(01)00926-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several examples of racemization process at a quaternary carbon center affecting Michael adducts were reported. A brief statement to prevent the occurrence of the interfering retro-Michael reaction was also presented. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5021 / 5023
页数：3
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