Electrochemical bisphenol A sensor based on N-doped graphene sheets

Bisphenol A (BPA), which could disrupt endocrine system and cause cancer, has been considered as an endocrine disruptor. Therefore, it is very important and necessary to develop a sensitive and selective method for detection of BPA. Herein, nitrogen-doped graphene sheets (N-GS) and chitosan (CS) were used to prepare electrochemical BPA sensor. Compared with graphene, N-GS has favorable electron transfer ability and electrocatalytic property, which could enhance the response signal towards BPA. CS also exhibits excellent film forming ability and improves the electrochemical behavior of N-GS modified electrode. The sensor exhibits a sensitive response to BPA in the range of 1.0 x 10(-8)-1.3 x 10(-6) mol L-1 with a low detection limit of 5.0 x 10(-9) mol L-1 under the optimal conditions. Finally, this proposed sensor was successfully employed to determine BRA in water samples with satisfactory results. (C) 2011 Elsevier B.V. All rights reserved.