Xestospongienols A-L, Brominated Acetylenic Acids from the Chinese Marine Sponge Xestospongia testudinaria

被引:0
|
作者
Liu, Dong [1 ]
Xu, Jing [1 ]
Jiang, Wei [1 ]
Deng, Zhiwei [2 ]
de Voogd, Nicole J. [3 ]
Proksch, Peter [4 ]
Lin, Wenhan [1 ]
机构
[1] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
[2] Beijing Normal Univ, Analyt & Testing Ctr, Beijing 100075, Peoples R China
[3] Natl Museum Nat Hist, NL-2300 Leiden, Netherlands
[4] Univ Dusseldorf, Inst Pharmaceut Biol & Biotechnol, D-40225 Dusseldorf, Germany
关键词
HARE APLYSIA-DACTYLOMELA; NATURAL-PRODUCTS; FATTY-ACIDS; LIPIDS; ETHER;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemical examination of the Chinese marine sponge Xestospongia testudinaria resulted in the isolation and characterization of twelve new brominated acetylenic acids, namely xestospongienols A-L (1a-1d, 2a-2d, and 3a-3d), together with the known analog 4. The structures of xestospongienols A-L were determined on the basis of 1D- and 2D-NMR, IR, and MS analysis in association with the modified Mosher method. The structural patterns are characteristic of brominated unbranched C(16)-alkyl chains containing polyene and acetylene moieties.
引用
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页码:1600 / 1607
页数:8
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