A novel and highly stereoselective intramolecular formal [3+3] cycloaddition reaction of vinylogous amides tethered with α,β-unsaturated aldehydes:: A formal total synthesis of (+)-gephyrotoxin

被引：0
|
作者：
Wei, LL [1 ]
Hsung, RP [1 ]
Sklenicka, HM [1 ]
Gerasyuto, AI [1 ]
机构：
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2001年 / 40卷 / 08期
关键词：
D O I：
10.1002/1521-3773(20010417)40:8<1516::AID-ANIE1516>3.0.CO;2-V
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Complex piperidinyl heterocycles (for example, 2) were accessed by using a novel intramolecular formal [3+3] cycloaddition reaction of vinylogous amides tethered with enals (for example, 1). This method has been applied to a formal total sythesis of (+)-gephyrotoxin (3).
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页码：1516 / +
页数：4
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