Concise synthesis of the tricyclic skeleton of cylindricines using a radical cascade involving 6-Endo selective cyclization

被引：27
|
作者：
Taniguchi, T
Tamura, O
Uchiyama, M
Muraoka, O
Tanabe, G
Ishibashi, H [1 ]
机构：
[1] Kanazawa Univ, Div Pharmaceut Sci, Grad Sch Nat Sci & Technol, Kanazawa, Ishikawa 9201192, Japan
[2] Kinki Univ, Fac Pharmaceut Sci, Osaka 5770818, Japan
来源：
SYNLETT | 2005年 / 07期
关键词：
cyclizations; cylindricine; regioselectivity; radical cascade; acyl radical;
D O I：
10.1055/s-2005-865236
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
On treatment with Bu3SnH and azobis(cyclohexanecarbonitrile) (ACN), enamide 19 underwent a 6-endo-trig/5-endo-trig radical cascade to afford perhydropyrrolo[2.1-j]quinoline derivative 21, a cylindricine skeleton.
引用
收藏
页码：1179 / 1181
页数：3
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