A formal synthesis of (+)-didemniserinolipid B employing a Pd-mediated 6-endo selective alkynediol cycloisomerization

被引：23
|
作者：
Ramana, C. V. [1 ]
Induvadana, Boddeti [1 ]
机构：
[1] Natl Chem Lab, Pune 411008, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 03期
关键词：
Didemniserinolipid; Bridged bicyclic ketal; Alkynol cycloisomerization; Zipper reaction; Yamaguchi oxirane alkyne coupling; NATURAL-PRODUCT; CATALYZED CYCLOISOMERIZATION; EFFICIENT METHOD; SUGAR ALKYNOLS; PALLADIUM; TRANSFORMATION; ACETALS; HYDROALKOXYLATION; CONFIGURATION; HETEROCYCLES;
D O I：
10.1016/j.tetlet.2008.10.137
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we describe a concise assembly of central 6,8-dioxabicyclo[3,2,1]octane core of didemniserino-lipid by employing a Pd-mediated alkynediol cycloisomerization and a formal total synthesis of didemniserinolipid (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：271 / 273
页数：3
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