In-Line Monitoring of Coating Thickness of Pharmaceutical Tablets during Production Scale Film Coating by Terahertz Imaging

被引：0

作者：

May, Robert K. ^{[1
]}

Evans, Michael J. ^{[2
]}

Zhong, Shuncong ^{[3
]}

Warr, Ian ^{[4
]}

Gladden, Lynn F. ^{[1
]}

Shen, Yaochun ^{[3
]}

Zeitler, J. Axel ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem Engn & Biotechnol, Cambridge CB2 3RA, England

[2] TeraView Ltd, Cambridge CB4 0WS, England

[3] Univ Liverpool, Dept Elect & Elect Engn, Liverpool L69 3GJ, Merseyside, England

[4] Oystar Mannesty, Liverpool L34 9JS, Merseyside, England

来源：

35TH INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER, AND TERAHERTZ WAVES (IRMMW-THZ 2010) | 2010年

关键词：

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We present preliminary results from in-line Terahertz pulsed imaging (TPI) measurements of coating thickness on pharmaceutical tablets made during production-scale film coating. Results of these real-time TPI measurements are compared to those from off-line TPI measurements, as well as weight-gain measurements made on sample tablets removed at discrete time-intervals during production. The results, and their repeatability, demonstrate that real-time monitoring of pharmaceutical tablet coating is not only possible but provides substantially more information than the standard quality control method.

引用

页数：2

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