A simulation tool for mechanical circulatory support device interaction with diseased states

被引：6
|
作者：
Horvath, David J. [1 ]
Horvath, Dennis W. [1 ]
Karimov, Jamshid H. [2 ]
Kuban, Barry D. [3 ]
Miyamoto, Takuma [2 ]
Fukamachi, Kiyotaka [2 ]
机构：
[1] R1 Engn, Euclid, OH USA
[2] Cleveland Clin, Lerner Res Inst, Dept Biomed Engn ND20, 9500 Euclid Ave, Cleveland, OH 44195 USA
[3] Cleveland Clin, Elect Core, Cleveland, OH 44106 USA
来源：
JOURNAL OF ARTIFICIAL ORGANS | 2020年 / 23卷 / 02期
关键词：
Cardiovascular disease; Computer simulation; Mock circulation loop; Lumped parameter; Pumps; Heart assist; CARDIOVASCULAR DYNAMICS; NUMERICAL-SIMULATION; LOOP;
D O I：
10.1007/s10047-020-01155-2
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We have created a simulation model to investigate the interactions between a variety of mechanical circulatory support (MCS) devices and the circulatory system with various simulated patient conditions and disease states. The present simulation accommodates a family of continuous-flow MCS devices under various stages of consideration or development at our institution. This article describes the mathematical core of the in silico simulation system and shows examples of simulation output imitating various disease states and of selected in vitro and clinical data from the literature.
引用
收藏
页码：124 / 132
页数：9
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