Antimicrobial Activity of Alternanthera brasiliana Kuntze (Amaranthaceae): a Biomonitored Study

被引：0
|
作者：
da Silva, Luciane C. [1 ]
Pegoraro, Kamm A. [1 ]
Pereira, Airton V. [1 ]
Esmerino, Luiz A. [2 ]
Cass, Quezia B. [3 ]
Barison, Anderson [4 ]
Beltrame, Flavio L. [1 ]
机构：
[1] Univ Estadual Ponta Grossa, Lab Tecnol Farmaceut, Dept Ciencias Farmaceut, BR-84030900 Ponta Grossa, PR, Brazil
[2] Univ Estadual Ponta Grossa, Microbiol Lab, Dept Anal Clin, BR-84030900 Ponta Grossa, PR, Brazil
[3] Univ Fed Sao Carlos UFSCar, Lab Cromatog Liquida & Sintese, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil
[4] Univ Fed Parana UFPr, Ctr Politecn, Lab Ressonancia Magnet Nucl, Dept Quim, BR-80060000 Curitiba, Parana, Brazil
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2011年 / 30卷 / 01期
关键词：
Alternanthera brasiliana; Bioautography; Microbiology; Quercetin; Sitosterol Glycoside; PLANT-EXTRACTS;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
In an attempt to identify new antimicrobial compounds with potential to be used as a bactericidal/fungicidal agent, a biomonitored study of extracts of Alternanthera brasiliana, which is used in Brazilian folk medicine as bactericidal, analgesic and anti-inflammatory, was developed. Different techniques of evaluation have been used in the partitioned extracts of the antimicrobial activity associated with chromatographic methodologies. The work led to the isolation of two substances in the ethyl acetate extract, identified as quercetin and sitosterol glycoside and the antibacterial evaluation of these substances demonstrated that the flavonoid presented antibacterial action against S. aureus. Further studies intend to identify new substances with antibacterial activity in extracts of A. brasiliana.
引用
收藏
页码：147 / 153
页数：7
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