CHEMICAL STUDY AND ANTIBACTERIAL ACTIVITY OF STEM OF Aristolochia esperanzae Kuntze (ARISTOLOCHIACEAE)

被引:12
|
作者
Pacheco, Alison G. [1 ]
Silva, Thiago M. [1 ]
Manfrini, Rozangela M. [1 ]
Sallum, William S. T. [1 ]
Duarte, Lucienir Pains [1 ]
Pilo-Veloso, Dorila [1 ]
Alcantara, Antonio F. de C. [1 ]
Knupp, Vagner F. [2 ]
机构
[1] Univ Fed Minas Gerais, Inst Ciencias Exatas, Dept Quim, BR-31260901 Belo Horizonte, MG, Brazil
[2] Fundacao Ctr Tecnol Minas Gerais, BR-31170000 Belo Horizonte, MG, Brazil
来源
QUIMICA NOVA | 2010年 / 33卷 / 08期
关键词
Aristolochia esperanzae; aristolochic acids; antibacterial activity; C-13; NMR-SPECTROSCOPY; ACIDS; DITERPENES; MEDICINE;
D O I
10.1590/S0100-40422010000800006
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
CHEMICAL STUDY AND ANTIBACTERIAL ACTIVITY OF STEM OF Aristolochia esperanzae Kuntze (ARISTOLOCHIACEAE). From the ethanolic extract of the stem of A. esperanzae ethyl and methyl fatty acid esters, fatty acids, aristolochic I and II acids, and beta-cubebin were isolated. In addiction asarinin, populifolic and 2-oxo-populifolic acids, aristolactams AIa and AII, and sitosterol 3-O-beta-D-glucopyranoside were also isolated and firstly described in the species. Asarinin and beta-cubebin showed antibacterial activity against Bacillus cereus and aristolochic acid I against Staphylococcus aureus and Listeria monocitogenes.
引用
收藏
页码:1649 / U53
页数:29
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