Recent Progress Concerning the N-Arylation of Indoles

被引：16

作者：

Oeser, Petr ^{[1
]}

Koudelka, Jakub ^{[1
]}

Petrenko, Artem ^{[1
]}

Tobrman, Tomas ^{[1
]}

机构：

[1] Univ Chem & Technol, Dept Organ Chem, Prague 16628, Czech Republic

来源：

MOLECULES | 2021年 / 26卷 / 16期

关键词：

N-arylation; indole; Buchwald-Hartwig amination; Ullmann condensation; Chan-Lam coupling; ASYMMETRIC ALLYLIC DEAROMATIZATION; EFFICIENT HETEROGENEOUS CATALYST; BUCHWALD-HARTWIG AMINATION; HIGH THERMAL-STABILITY; C-H; HIGHLY EFFICIENT; ARYL HALIDES; ENANTIOSELECTIVE SYNTHESIS; COUPLING REACTIONS; AT(1) ANTAGONISTS;

D O I：

10.3390/molecules26165079

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles.

引用

页数：44

共 50 条

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