Ultrastructure of the Effects of Pyrrolidine-fused Chlorins on the Replication of HSV-1

被引：0

作者：

Matos, Antonio P. A. ^{[1
,2
]}

Santos, Ana R. N. ^{[3
]}

Caeiro, Maria F. ^{[4
,5
]}

Faustino, Maria A. F. ^{[3
]}

Neves, M. G. P. M. S. ^{[3
]}

Tome, A. C. ^{[3
]}

Cavaleiro, Jose A. S. ^{[3
]}

机构：

[1] Univ Lisbon, Sch Dent Med, P-1649003 Lisbon, Portugal

[2] Curry Cabral Hosp, P-1069166 Lisbon, Portugal

[3] Univ Aveiro, Dept Chem, P-3810193 Aveiro, Portugal

[4] Univ Lisbon, Fac Sci, Dept Plant Biol, P-1749016 Lisbon, Portugal

[5] Univ Lisbon, Environm Biol Ctr, P-1749016 Lisbon, Portugal

来源：

MICROSCOPY AND MICROANALYSIS | 2008年 / 14卷

关键词：

D O I：

10.1017/S1431927608089666

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Currently, only few antiviral drugs of proven effectiveness exist against virus of the Herpesviridae family and viral resistance to these drugs, especially in the immunocompromised hosts, has encouraged research for new drugs. Some porphyrin derivatives revealed a significant antiviral activity against HSV-1 virus. However the cellular target of the porphyrin derivatives in the virus-cell complex remains unknown. © 2008 Microscopy Society of America.

引用

页码：137 / 138

页数：2

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