TNF-α ENHANCES HUMAN REGULATORY T CELL FUNCTION VIA TNFR2: A NEW STRATEGY TO IMPROVE GVHD PREVENTION

被引：0
|
作者：
Mancusi, A. [1 ]
Piccinelli, S. [1 ]
Zei, T. [1 ]
Ostini, R. Iacucci [1 ]
Falzetti, F. [1 ]
Velardi, A. [1 ]
Pierini, A. [1 ]
机构：
[1] Univ Perugia, Sez Ematol & Immunol Clin, Dipartimento Med, Perugia, Italy
来源：
HAEMATOLOGICA | 2018年 / 103卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
CO033
引用
收藏
页码：S35 / S35
页数：1
相关论文
共 50 条
  • [41] TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway
    Wang, Jun
    Ferreira, Ricardo
    Lu, Wanhua
    Farrow, Samatha
    Downes, Kate
    Jermutus, Lutz
    Minter, Ralph
    Al-Lamki, Rafia S.
    Pober, Jordan S.
    Bradley, John R.
    SCIENTIFIC REPORTS, 2018, 8
  • [42] Association of the tumor necrosis factor-alpha (TNF-α) and its receptor 2 (TNFR2) genes with human narcolepsy.
    Hohjoh, H
    Terada, N
    Kawashima, M
    Honda, Y
    Tokunaga, K
    AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) : 354 - 354
  • [43] TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application
    Mahsa Nouri Barkestani
    Sara Shamdani
    Mazdak Afshar Bakshloo
    Nassim Arouche
    Bijan Bambai
    Georges Uzan
    Sina Naserian
    Cell Communication and Signaling, 19
  • [44] Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma
    Tomolonis, Julie A.
    Xu, Xin
    Dholakia, Kshiti H.
    Zhang, Chunchao
    Guo, Linjie
    Courtney, Amy N.
    Wang, Siyue
    Balzeau, Julien
    Barragan, Gabriel A.
    Tian, Gengwen
    Di Pierro, Erica J.
    Metelitsa, Leonid S.
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (03)
  • [45] TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application
    Nouri Barkestani, Mahsa
    Shamdani, Sara
    Afshar Bakshloo, Mazdak
    Arouche, Nassim
    Bambai, Bijan
    Uzan, Georges
    Naserian, Sina
    CELL COMMUNICATION AND SIGNALING, 2021, 19 (01)
  • [46] Anti-TNF Antibodies Target T-Cell Apoptosis in Inflammatory Bowel Diseases via the mTNF/TNFR2 Signalling Pathway
    Atreya, Raja
    Zimmer, Michael
    Bartsch, Brigitte
    Waldner, Maximilian J.
    Atreya, Imke
    Neumann, Helmut
    Mudter, Jonas
    Hildner, Kai
    Hoffman, Arthur
    Kiesslich, Ralf
    Rose-John, Stefan
    Rink, Andreas D.
    Schmidt, Jan
    Neurath, Markus F.
    GASTROENTEROLOGY, 2011, 140 (05) : S838 - S838
  • [47] TGF-β renders in vivo regulatory T cell function independent of TNF-α
    Housley, William
    Adams, Catherine
    Nichols, Frank
    Puddington, Lynn
    Lingenheld, Elizabeth
    Zhu, Li
    Ragan, Thiruchandurai
    Clark, Robert
    JOURNAL OF IMMUNOLOGY, 2011, 186
  • [48] TNFR2 Costimulation Differentially Impacts Regulatory and Conventional CD4+ T-Cell Metabolism
    Mensink, Mark
    Tran, Thi Ngoc Minh
    Zaal, Esther A.
    Schrama, Ellen
    Berkers, Celia R.
    Borst, Jannie
    de Kivit, Sander
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [49] Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells
    Masaki Inoue
    Yuta Tsuji
    Reira Ueno
    Daisuke Miyamoto
    Keisuke Tanaka
    Yuka Moriyasu
    Saya Shibata
    Mei Okuda
    Daisuke Ando
    Yasuhiro Abe
    Haruhiko Kamada
    Shin-ichi Tsunoda
    Scientific Reports, 13
  • [50] TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40
    Hamano, Ryoko
    Huang, Jiaqiang
    Yoshimura, Teizo
    Oppenheim, Joost J.
    Chen, Xin
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2011, 41 (07) : 2010 - 2020
12345