TNF-α ENHANCES HUMAN REGULATORY T CELL FUNCTION VIA TNFR2: A NEW STRATEGY TO IMPROVE GVHD PREVENTION

被引：0
|
作者：
Mancusi, A. [1 ]
Piccinelli, S. [1 ]
Zei, T. [1 ]
Ostini, R. Iacucci [1 ]
Falzetti, F. [1 ]
Velardi, A. [1 ]
Pierini, A. [1 ]
机构：
[1] Univ Perugia, Sez Ematol & Immunol Clin, Dipartimento Med, Perugia, Italy
来源：
HAEMATOLOGICA | 2018年 / 103卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
CO033
引用
收藏
页码：S35 / S35
页数：1
相关论文
共 50 条
  • [21] Blockade of TNF-α/TNFR2 signalling suppresses colorectal cancer and enhances the efficacy of anti-PD1 immunotherapy by decreasing CCR8+T regulatory cells
    Guo, Yixian
    Xie, Feng
    Liu, Xu
    Ke, Shouyu
    Chen, Jieqiong
    Zhao, Yi
    Li, Ning
    Wang, Zeyu
    Yi, Gang
    Shen, Yanying
    Li, Dan
    Zhu, Chunchao
    Zhang, Zizhen
    Zhao, Gang
    Lu, Hong
    Li, Bin
    Zhao, Wenyi
    JOURNAL OF MOLECULAR CELL BIOLOGY, 2024, 16 (06)
  • [22] The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect
    Naserian, Sina
    Abdelgawad, Mohamed Essameldin
    Bakshloo, Mazdak Afshar
    Ha, Guillaume
    Arouche, Nassim
    Cohen, Jose L.
    Salomon, Benoit L.
    Uzan, Georges
    CELL COMMUNICATION AND SIGNALING, 2020, 18 (01)
  • [23] The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect
    Sina Naserian
    Mohamed Essameldin Abdelgawad
    Mazdak Afshar Bakshloo
    Guillaume Ha
    Nassim Arouche
    José L. Cohen
    Benoît L. Salomon
    Georges Uzan
    Cell Communication and Signaling, 18
  • [24] Regulatory T cell induction by mesenchymal stem cells depends on the expression of TNFR2 by T cells
    Sina Naserian
    Sara Shamdani
    Nassim Arouche
    Georges Uzan
    Stem Cell Research & Therapy, 11
  • [25] Use of tumor necrosis factor receptor 2 (TNFR2)/p75 and TNF-α as an antitumor strategy.
    Bae, Sanggyu
    Sasi, Sharath
    Song, Jin
    Perepletchikov, Aleksandr
    Arid, Douglas Schneider
    Goukassian, David
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [26] Antagonistic Antibody Targeting TNFR2 Inhibits Regulatory T Cell Function to Promote Anti-Tumor Activity
    Chen, Yonglin
    Jia, Manxue
    Wang, Sharon
    Xu, Sherry
    He, Nanhai
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [27] Regulatory T cell induction by mesenchymal stem cells depends on the expression of TNFR2 by T cells
    Naserian, Sina
    Shamdani, Sara
    Arouche, Nassim
    Uzan, Georges
    STEM CELL RESEARCH & THERAPY, 2020, 11 (01)
  • [28] TNF-Alpha Priming Enhances CD4+ FoxP3+ Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment
    Pierini, Antonio
    Moffett, Caitlin
    Schneidawind, Dominik
    Baker, Jeanette
    Nishikii, Hidekazu
    Pan, Yuqiong
    Alvarez, Maite
    Meyer, Everett
    Negrin, Robert
    BLOOD, 2015, 126 (23)
  • [29] Interaction of TNF and TNFR2 stabilizes the phenotype and function of CD4+FoxP3+regulatory T cells in the inflammatory environment
    Chen, Xin
    Wu, Xueqiang
    Howard, O. M. Zack
    Oppenheim, Joost
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [30] Human TNFR2 Exhibits Bi-Directional Control over Regulatory T Cells
    Faustman, Denise L.
    Wang, Limei
    Okubo, Yoshiaki
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB398 - AB398
12345