A minor capsid protein P30 is essential for bacteriophage PRD1 capsid assembly

被引：43
|
作者：
Rydman, PS
Bamford, JKH
Bamford, DH
机构：
[1] Univ Helsinki, Viikki Bioctr, Dept Biosci, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Viikki Bioctr, Inst Biotechnol, FIN-00014 Helsinki, Finland
来源：
JOURNAL OF MOLECULAR BIOLOGY | 2001年 / 313卷 / 04期
基金：
芬兰科学院;
关键词：
virus assembly; virus structure; membrane biogenesis; bacteriophage PRD1; capsid stability;
D O I：
10.1006/jmbi.2001.5068
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bacteriophage PRD1 is a double-stranded DNA virus infecting Gram-negative hosts. It has a membrane component located in the interior of the isometric capsid. In addition to the major capsid protein P3, the capsid contains a 9 kDa protein P30. Protein P30 is proposed to be located between the adjacent facets of the icosahedral capsid and is required for stable capsid assembly. In its absence, an empty phage-specific membrane vesicle is formed. The major protein component of this vesicle is a phage-encoded assembly factor, protein P10, that is not present in the final structure. (C) 2001 Academic Press.
引用
收藏
页码：785 / 795
页数：11
相关论文
共 50 条
  • [21] Efficient DNA packaging of bacteriophage PRD1 requires the unique vertex protein P6
    Karhu, Nelli J.
    Ziedaite, Gabija
    Bamford, Dennis H.
    Bamford, Jaana K. H.
    JOURNAL OF VIROLOGY, 2007, 81 (06) : 2970 - 2979
  • [22] OVERPRODUCTION, PURIFICATION, AND CHARACTERIZATION OF DNA-BINDING PROTEIN P19 OF BACTERIOPHAGE PRD1
    PAKULA, TM
    CALDENTEY, J
    GUTIERREZ, C
    OLKKONEN, VM
    SALAS, M
    BAMFORD, DH
    GENE, 1993, 126 (01) : 99 - 104
  • [23] Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein
    Chang, Jenny R.
    Spilman, Michael S.
    Dokland, Terje
    VIRUS GENES, 2010, 40 (02) : 298 - 306
  • [24] Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein
    Jenny R. Chang
    Michael S. Spilman
    Terje Dokland
    Virus Genes, 2010, 40 : 298 - 306
  • [25] The assembly factor P17 from bacteriophage PRD1 interacts with positively charged lipid membranes
    Holopainen, JM
    Säily, M
    Caldentey, J
    Kinnunen, PKJ
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 2000, 267 (20): : 6231 - 6238
  • [26] Integral membrane protein P16 of bacteriophage PRD1 stabilizes the adsorption vertex structure
    Jaatinen, ST
    Viitanen, SJ
    Bamford, DH
    Bamford, JKH
    JOURNAL OF VIROLOGY, 2004, 78 (18) : 9790 - 9797
  • [27] CAPSID LOCALIZATION OF THE BACTERIOPHAGE-P4 PSU PROTEIN
    DOKLAND, T
    ISAKSEN, ML
    FULLER, SD
    LINDQVIST, BH
    VIROLOGY, 1993, 194 (02) : 682 - 687
  • [28] Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein
    Bartonova, Vanda
    Igonet, Sebastien
    Sticht, Jana
    Glass, Baerbel
    Habermann, Anja
    Vaney, Marie-Christine
    Sehr, Peter
    Lewis, Joe
    Rey, Felix A.
    Kraeusslich, Hans-Georg
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (46) : 32024 - 32033
  • [29] Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures
    Benson, SD
    Bamford, JKH
    Bamford, DH
    Burnett, RM
    CELL, 1999, 98 (06) : 825 - 833
  • [30] The assembly-activating protein is essential for capsid assembly of AAV in insect cells
    Penaud-Budloo, M.
    Herrmann, A. K.
    Menard, L.
    Grosse, S.
    Grimm, D.
    Ayuso, E.
    HUMAN GENE THERAPY, 2017, 28 (12) : A109 - A109
12345