Assessing the Effects of Amoxicillin on Antioxidant Enzyme Activities, Lipid Peroxidation and Protein Carbonyl Content in the Clam Ruditapes philippinarum and the Mussel Mytilus galloprovincialis

被引:21
|
作者
Matozzo, Valerio [1 ]
Battistara, Margherita [1 ]
Marisa, Ilaria [1 ]
Bertin, Valeria [1 ]
Orsetti, Alessandro [2 ]
机构
[1] Univ Padua, Dept Biol, Via Ugo Bassi 58-B, I-35131 Padua, Italy
[2] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Via Marzolo 5, I-35131 Padua, Italy
关键词
Bivalve; Pharmaceutical; Antibiotic; Amoxicillin; Antioxidants; AFFECT HEMOCYTE PARAMETERS; ENVIRONMENTAL OCCURRENCE; AQUATIC ENVIRONMENT; PHARMACEUTICALS; ANTIBIOTICS; FATE; STRESS; PATHWAYS; EXPOSURE; AQUACULTURE;
D O I
10.1007/s00128-016-1902-8
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In this study, we evaluated the capability of amoxicillin (AMX)-one of the most widely used antibiotics worldwide-to induce oxidative stress in both gills and digestive gland from two bivalve species, the clam Ruditapes philippinarum and the mussel Mytilus galloprovincialis. Superoxide dismutase (SOD) and catalase (CAT) activities, as well as the lipid peroxidation levels (LPO) and protein carbonyl content (PCC), were measured in bivalves exposed to 100, 200 and 400 A mu g AMX/L for 1, 3 and 7 days. The results obtained demonstrated that AMX affected slightly biomarker responses of molluscs.
引用
收藏
页码:521 / 527
页数:7
相关论文
共 50 条
  • [41] Cadmium induction of lipid peroxidation and effects on root tip cells and antioxidant enzyme activities in Vicia faba L.
    Shanshan Zhang
    Huimin Zhang
    Rong Qin
    Wusheng Jiang
    Donghua Liu
    Ecotoxicology, 2009, 18 : 814 - 823
  • [42] Comparative study of alloxan effects in copper-loaded and iron-loaded rats: lipid peroxidation, protein oxidation, proteasome and antioxidant enzyme activities
    Alexandrova, Albena
    Georgieva, Almira
    Petrov, Lubomir
    Tsvetanova, Elina
    Kirkova, Margarita
    CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 2006, 1 (02): : 235 - 248
  • [43] Angiotensin Converting Enzyme and Dipeptidyl Peptidase-IV Inhibitory, and Antioxidant Activities of a Blue Mussel (Mytilus edulis) Meat Protein Extract and Its Hydrolysates
    Neves, Adriana C.
    Harnedy, Padraigin A.
    FitzGerald, Richard J.
    JOURNAL OF AQUATIC FOOD PRODUCT TECHNOLOGY, 2016, 25 (08) : 1221 - 1233
  • [45] Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action
    Mansour, MA
    Nagi, MN
    El-Khatib, AS
    Al-Bekairi, AM
    CELL BIOCHEMISTRY AND FUNCTION, 2002, 20 (02) : 143 - 151
  • [46] Water availability effects on antioxidant enzyme activities, lipid peroxidation, and reducing sugar contents of alfalfa (Medicago sativa L.)
    Boldaji, S. A. Hosseini
    Khavari-Nejad, R. A.
    Sajedi, R. Hassan
    Fahimi, H.
    Saadatmand, S.
    ACTA PHYSIOLOGIAE PLANTARUM, 2012, 34 (03) : 1177 - 1186
  • [47] Joint effects of Penta-BDE and heavy metals on Daphnia magna survival, its antioxidant enzyme activities and lipid peroxidation
    Baohua Tang
    Lingyan Zhu
    Qixing Zhou
    Frontiers of Environmental Science & Engineering in China, 2011, 5 : 99 - 110
  • [48] Joint effects of Penta-BDE and heavy metals on Daphnia magna survival, its antioxidant enzyme activities and lipid peroxidation
    Tang, Baohua
    Zhu, Lingyan
    Zhou, Qixing
    FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING IN CHINA, 2011, 5 (01): : 99 - 110
  • [49] Water availability effects on antioxidant enzyme activities, lipid peroxidation, and reducing sugar contents of alfalfa (Medicago sativa L.)
    S. A. Hosseini Boldaji
    R. A. Khavari-Nejad
    R. Hassan Sajedi
    H. Fahimi
    S. Saadatmand
    Acta Physiologiae Plantarum, 2012, 34 : 1177 - 1186
  • [50] Effects of trimetazidine on lipid peroxidation, antioxidant enzyme activities and plasma brain natriuretic peptide levels in patients with chronic cor pulmonale
    Bayram, E
    Atalay, C
    Kocatürk, H
    Yücel, O
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2005, 33 (06) : 612 - 619