Assessing the Effects of Amoxicillin on Antioxidant Enzyme Activities, Lipid Peroxidation and Protein Carbonyl Content in the Clam Ruditapes philippinarum and the Mussel Mytilus galloprovincialis

被引:21
|
作者
Matozzo, Valerio [1 ]
Battistara, Margherita [1 ]
Marisa, Ilaria [1 ]
Bertin, Valeria [1 ]
Orsetti, Alessandro [2 ]
机构
[1] Univ Padua, Dept Biol, Via Ugo Bassi 58-B, I-35131 Padua, Italy
[2] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Via Marzolo 5, I-35131 Padua, Italy
关键词
Bivalve; Pharmaceutical; Antibiotic; Amoxicillin; Antioxidants; AFFECT HEMOCYTE PARAMETERS; ENVIRONMENTAL OCCURRENCE; AQUATIC ENVIRONMENT; PHARMACEUTICALS; ANTIBIOTICS; FATE; STRESS; PATHWAYS; EXPOSURE; AQUACULTURE;
D O I
10.1007/s00128-016-1902-8
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In this study, we evaluated the capability of amoxicillin (AMX)-one of the most widely used antibiotics worldwide-to induce oxidative stress in both gills and digestive gland from two bivalve species, the clam Ruditapes philippinarum and the mussel Mytilus galloprovincialis. Superoxide dismutase (SOD) and catalase (CAT) activities, as well as the lipid peroxidation levels (LPO) and protein carbonyl content (PCC), were measured in bivalves exposed to 100, 200 and 400 A mu g AMX/L for 1, 3 and 7 days. The results obtained demonstrated that AMX affected slightly biomarker responses of molluscs.
引用
收藏
页码:521 / 527
页数:7
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