Biomarkers of laryngeal squamous cell carcinoma: a review

被引：29
|
作者：
Cavaliere, Matteo [1 ]
Bisogno, Antonella [1 ]
Scarpa, Alfonso [1 ]
D'Urso, Alessia [1 ]
Marra, Pasquale [1 ]
Colacurcio, Vito [1 ]
De Luca, Pietro [1 ]
Ralli, Massimo [2 ]
Cassandro, Ettore [1 ]
Cassandro, Claudia [3 ]
机构：
[1] Univ Salerno, Dept Med & Surg, Via Salvador Allende 43, I-84081 Salerno, Italy
[2] Sapienza Univ Rome, Dept Sense Organs, Viale Policlin 155, I-00161 Rome, Italy
[3] Univ Turin, Surg Sci Dept, Corso Dogliotti 14, I-10124 Turin, Italy
来源：
ANNALS OF DIAGNOSTIC PATHOLOGY | 2021年 / 54卷
关键词：
Laryngeal neoplasms; RNA; long noncoding; Ki-67; antigen; Focal adhesion protein-tyrosine kinases; Cyclin D1; Tumour suppressor protein p53; Cadherins; Receptors; growth factor; E-CADHERIN EXPRESSION; FOCAL-ADHESION KINASE; PREDICTS RADIOTHERAPY FAILURE; FACTOR RECEPTOR EXPRESSION; KI-67; ANTIGEN-EXPRESSION; LYMPH-NODE METASTASES; PROGNOSTIC-SIGNIFICANCE; GROWTH-FACTOR; HUMAN-PAPILLOMAVIRUS; BCL-2; EXPRESSION;
D O I：
10.1016/j.anndiagpath.2021.151787
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Laryngeal carcinoma is the second common malignancy of the upper aerodigestive tract after lung cancer; in most cases is a squamous cell carcinoma, whose risk factors include tobacco smoking and alcohol consumption. Despite therapeutic progress, the five-year overall survival rate for this malignancy has remained nearly 50% and many patients already present metastasis at the time of diagnosis. To date, there are no tools that predict the evolution of laryngeal carcinoma: in this light, during the last years, many studies were planned with the aim to investigate the role played by different biomarkers expressed by larynx cancer, which can help make an early diagnosis, predict disease evolution and direct therapeutic choice. This review aims to summarize these markers and correlating them with disease evolution.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Biomarkers in Laryngeal Squamous Cell Carcinoma: The Literature Review
    Verro, Barbara
    Saraniti, Carmelo
    Carlisi, Daniela
    Chiesa-Estomba, Carlos
    Maniaci, Antonino
    Lechien, Jerome R.
    Mayo, Miguel
    Fakhry, Nicolas
    Lauricella, Marianna
    [J]. CANCERS, 2023, 15 (20)
  • [2] Correlation of Histopathological Findings in Laryngeal Squamous Cell Carcinoma with Inflammatory Biomarkers
    Deveci, Ildem
    Surmeli, Mehmet
    Onder, Serap
    Karabulut, Burak
    Deveci, Hande Senem
    Oysu, Cagatay
    [J]. ENT UPDATES, 2019, 9 (01): : 44 - 52
  • [3] Potentials of lncRNA–miRNA–mRNA networks as biomarkers for laryngeal squamous cell carcinoma
    Yan Lv
    Yanhua Wang
    Zhikai Zhang
    [J]. Human Cell, 2023, 36 : 76 - 97
  • [4] Prognostic Analysis of Preoperative Inflammatory Biomarkers in Patients With Laryngeal Squamous Cell Carcinoma
    Xun, Youfang
    Wang, Maohua
    Sun, Haiyong
    Shi, Shujun
    Guan, Bing
    Yu, Chenjie
    [J]. ENT-EAR NOSE & THROAT JOURNAL, 2020, 99 (06) : 371 - 378
  • [5] LARYNGEAL SARCOCYSTOSIS ACCOMPANYING LARYNGEAL SQUAMOUS CELL CARCINOMA: CASE REPORT AND LITERATURE REVIEW
    Larbcharoensub, Noppadol
    Cheewaruangroj, Wichit
    Nitiyanant, Prawat
    [J]. SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH, 2011, 42 (05) : 1072 - 1076
  • [6] Prognostic value of cell-cycle regulators and cellular biomarkers in laryngeal squamous cell carcinoma
    Swellam, Menha
    El-Arab, Lobna R. Ezz
    Adly, Ahmed
    [J]. CLINICAL BIOCHEMISTRY, 2008, 41 (13) : 1059 - 1066
  • [7] Histogenesis of laryngeal squamous cell carcinoma
    Kleinsasser, O
    Grzonka, M
    Nickol, T
    Dederichs, G
    [J]. HEAD AND NECK CANCER - ADVANCES IN BASIC RESEARCH, 1996, 1114 : 413 - 416
  • [8] Laryngeal spindle cell squamous cell carcinoma
    Thompson, Lester D. R.
    [J]. ENT-EAR NOSE & THROAT JOURNAL, 2011, 90 (05) : 214 - +
  • [9] Paediatric laryngeal squamous cell carcinoma: Systematic review and pooled analysis
    Mur, Taha
    Jaleel, Zaroug
    Agarwal, Pratima
    Edwards, Heather
    Levi, Jessica R.
    [J]. CLINICAL OTOLARYNGOLOGY, 2021, 46 (03) : 494 - 500
  • [10] Human papillomavirus infection and its biomarkers' expressions in laryngeal basaloid squamous cell carcinoma
    Cui, Lifang
    Qu, Congling
    Liu, Honggang
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2018, 11 (11): : 5379 - 5386
12345