Biomarkers of laryngeal squamous cell carcinoma: a review

被引：34
|
作者：
Cavaliere, Matteo [1 ]
Bisogno, Antonella [1 ]
Scarpa, Alfonso [1 ]
D'Urso, Alessia [1 ]
Marra, Pasquale [1 ]
Colacurcio, Vito [1 ]
De Luca, Pietro [1 ]
Ralli, Massimo [2 ]
Cassandro, Ettore [1 ]
Cassandro, Claudia [3 ]
机构：
[1] Univ Salerno, Dept Med & Surg, Via Salvador Allende 43, I-84081 Salerno, Italy
[2] Sapienza Univ Rome, Dept Sense Organs, Viale Policlin 155, I-00161 Rome, Italy
[3] Univ Turin, Surg Sci Dept, Corso Dogliotti 14, I-10124 Turin, Italy
来源：
ANNALS OF DIAGNOSTIC PATHOLOGY | 2021年 / 54卷
关键词：
Laryngeal neoplasms; RNA; long noncoding; Ki-67; antigen; Focal adhesion protein-tyrosine kinases; Cyclin D1; Tumour suppressor protein p53; Cadherins; Receptors; growth factor; E-CADHERIN EXPRESSION; FOCAL-ADHESION KINASE; PREDICTS RADIOTHERAPY FAILURE; FACTOR RECEPTOR EXPRESSION; KI-67; ANTIGEN-EXPRESSION; LYMPH-NODE METASTASES; PROGNOSTIC-SIGNIFICANCE; GROWTH-FACTOR; HUMAN-PAPILLOMAVIRUS; BCL-2; EXPRESSION;
D O I：
10.1016/j.anndiagpath.2021.151787
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Laryngeal carcinoma is the second common malignancy of the upper aerodigestive tract after lung cancer; in most cases is a squamous cell carcinoma, whose risk factors include tobacco smoking and alcohol consumption. Despite therapeutic progress, the five-year overall survival rate for this malignancy has remained nearly 50% and many patients already present metastasis at the time of diagnosis. To date, there are no tools that predict the evolution of laryngeal carcinoma: in this light, during the last years, many studies were planned with the aim to investigate the role played by different biomarkers expressed by larynx cancer, which can help make an early diagnosis, predict disease evolution and direct therapeutic choice. This review aims to summarize these markers and correlating them with disease evolution.
引用
收藏
页数：10
相关论文
共 50 条
  • [41] Update of prognostic and predictive biomarkers in oropharyngeal squamous cell carcinoma: a review
    Grimminger, Carolin M.
    Danenberg, Peter V.
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2011, 268 (01) : 5 - 16
  • [42] Simultaneous Laryngeal Squamous Cell Carcinoma and Papillary Thyroid Carcinoma
    Ashraf, Mohamad Javad
    Alavi, Mehr Sadat
    Azarpira, Negar
    Khademi, Bighan
    MIDDLE EAST JOURNAL OF CANCER, 2011, 2 (02) : 87 - 90
  • [43] An unusual variant of laryngeal squamous cell carcinoma: condylomatous carcinoma
    Acar, G. Oezbilen
    Toprak, M.
    Oez, B.
    Bozkurt, S. Uyar
    TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY, 2010, 48 (02) : 89 - 93
  • [44] WNT pathway in laryngeal squamous cell carcinoma and nasopharyngeal carcinoma
    Galera-Ruiz, H.
    Rios-Moreno, M. J.
    Gonzalez-Campora, R.
    Galera-Davidson, H.
    ACTA OTORHINOLARYNGOLOGICA ITALICA, 2012, 32 (02) : 122 - 123
  • [45] LncRNA-Associated ceRNA Network Reveals Novel Potential Biomarkers of Laryngeal Squamous Cell Carcinoma
    Jing, Zhibin
    Guo, Sitong
    Zhang, Peng
    Liang, Zheng
    TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 2020, 19
  • [46] A Critical Review on microRNAs as Prognostic Biomarkers in Laryngeal Carcinoma
    Komitova, Kristina S.
    Dimitrov, Lyuben D.
    Stancheva, Gergana S.
    Kyurkchiyan, Silva G.
    Petkova, Veronika
    Dimitrov, Stoyan I.
    Skelina, Silviya P.
    Kaneva, Radka P.
    Popov, Todor M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (24)
  • [47] Predicting biomarkers in laryngeal squamous cell carcinoma based on the cytokine-cytokine receptor interaction pathway
    Chen, Qingyong
    Wang, Dongqing
    Chen, Zhipeng
    Lin, Liqiang
    Shao, Qiang
    Zhang, Han
    Li, Peng
    Lv, Huaiqing
    HELIYON, 2024, 10 (18)
  • [48] Occult Metastasis in Laryngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
    Sharbel, Daniel D.
    Abkemeier, Mary
    Groves, Michael W.
    Albergotti, William G.
    Byrd, J. Kenneth
    Reyes-Gelves, Camilo
    ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2021, 130 (01): : 67 - 77
  • [49] Pitfalls in the Staging of Cancer of the Laryngeal Squamous Cell Carcinoma
    Baugnon, Kristen L.
    Beitler, Jonathan J.
    NEUROIMAGING CLINICS OF NORTH AMERICA, 2013, 23 (01) : 81 - +
  • [50] Markers for nodal metastasis in laryngeal squamous cell carcinoma
    Kulagin, R.
    Semyon, P.
    Anas, U.
    VIRCHOWS ARCHIV, 2011, 459 : S113 - S113
12345