Chiral separation of β2-blockers on pirkle-type chiral stationary phases

被引：11
|
作者：
Zhang, DD
Li, FM
Hyun, MH [1 ]
机构：
[1] Pusan Natl Univ, Dept Chem, Pusan 609735, South Korea
[2] Pusan Natl Univ, Chem Inst Funct Mat, Pusan 609735, South Korea
[3] Shenyang Pharmaceut Univ, Dept Analyt Chem, Shenyang, Peoples R China
来源：
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2005年 / 28卷 / 02期
关键词：
enantiomer separation; beta(2)-blockers; chiral stationary phases;
D O I：
10.1081/JLC-200041279
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Liquid chromatographic resolution of six racemic beta(2)-blockers including bambuterol, clenbuterol, clenpropol, fumoterol, mabuterol, and terbutaline was studied on two Pirkle-type chiral stationary phases (CSPs) such as alpha-Burke-2 and Pirkle-1J. By varying the mobile phase compositions, five of the six beta(2)-blockers were successfully resolved on alpha-Burke-2 CSP, while only two beta(2)-blockers were resolved on Pirkle-1J CSP.
引用
收藏
页码：187 / 198
页数：12
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