Chiral separation of β2-blockers on pirkle-type chiral stationary phases

被引：11

作者：

Zhang, DD

Li, FM

Hyun, MH ^{[1
]}

机构：

[1] Pusan Natl Univ, Dept Chem, Pusan 609735, South Korea

[2] Pusan Natl Univ, Chem Inst Funct Mat, Pusan 609735, South Korea

[3] Shenyang Pharmaceut Univ, Dept Analyt Chem, Shenyang, Peoples R China

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2005年 / 28卷 / 02期

关键词：

enantiomer separation; beta(2)-blockers; chiral stationary phases;

D O I：

10.1081/JLC-200041279

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Liquid chromatographic resolution of six racemic beta(2)-blockers including bambuterol, clenbuterol, clenpropol, fumoterol, mabuterol, and terbutaline was studied on two Pirkle-type chiral stationary phases (CSPs) such as alpha-Burke-2 and Pirkle-1J. By varying the mobile phase compositions, five of the six beta(2)-blockers were successfully resolved on alpha-Burke-2 CSP, while only two beta(2)-blockers were resolved on Pirkle-1J CSP.

引用

页码：187 / 198

页数：12

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