The Mediator of Hematopoietic Stem Cell Homeostasis

被引：0
|
作者：
Borikar, Sneha [1 ]
Trowbridge, Jennifer J. [1 ]
机构：
[1] Jackson Lab Mammalian Genet, Bar Harbor, ME 04609 USA
来源：
Cell Stem Cell | 2016年 / 19卷 / 06期
关键词：
CHRONIC LYMPHOCYTIC-LEUKEMIA; MUTATIONS; MED12;
D O I：
10.1016/j.stem.2016.11.012
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Mechanisms establishing and maintaining promoter-enhancer interactions in hematopoietic stem cells (HSCs) to maintain stem cell identity are not fully understood. In this issue of Cell Stem Cell, Aranda-Orgilles et al. (2016) describe a role for a member of the Mediator complex in maintaining HSC-specific enhancers and hematopoietic homeostasis.
引用
收藏
页码：677 / 678
页数：2
相关论文
共 50 条
  • [41] THYMIC FUNCTION AND T CELL HOMEOSTASIS AFTER HAPLOIDENTICAL ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
    Butera, S.
    Lia, G.
    Evangelista, A.
    Tosti, L.
    Comba, L.
    Cena, S.
    Pulito, R.
    Brunello, L.
    Gilestro, M.
    Ruggeri, M.
    Oddolo, D.
    Caltagirone, S. A.
    Muccio, V. E.
    Saraci, E.
    Festuccia, M.
    Ciccone, G.
    Maffini, E.
    Dellacasa, C.
    Boccadoro, M.
    Giaccone, L.
    Busca, A.
    Omede, P. M.
    Bruno, B.
    HAEMATOLOGICA, 2018, 103 : S37 - S37
  • [42] Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis
    Rodrigues, NP
    Janzen, V
    Forkert, R
    Dombkowski, DM
    Boyd, AS
    Orkin, SH
    Enver, T
    Vyas, P
    Scadden, DT
    BLOOD, 2005, 106 (02) : 477 - 484
  • [43] Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis
    Zhang, Chao
    Yi, Weiwei
    Li, Fei
    Du, Xufei
    Wang, Hu
    Wu, Ping
    Peng, Chao
    Luo, Man
    Hua, Wen
    Wong, Catherine C. L.
    Lee, James J.
    Li, Wen
    Chen, Zhihua
    Ying, Songmin
    Ju, Zhenyu
    Shen, Huahao
    CELL RESEARCH, 2018, 28 (03) : 323 - 335
  • [44] Interleukin 7 receptor is required for myeloid cell homeostasis and reconstitution by hematopoietic stem cells
    Cool, Taylor
    Worthington, Atesh
    Poscablo, Donna
    Hussaini, Adeel
    Forsberg, E. Camilla
    EXPERIMENTAL HEMATOLOGY, 2020, 90 : 39 - +
  • [45] Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice
    Helgason, CD
    Antonchuk, J
    Bodner, C
    Humphries, RK
    BLOOD, 2003, 102 (10) : 3541 - 3547
  • [46] Small noncoding RNAs play superior roles in maintaining hematopoietic stem cell homeostasis
    Wang, Hui
    Qian, Wenchang
    Han, Yingli
    Qian, Pengxu
    BLOOD SCIENCE, 2022, 4 (03): : 125 - 132
  • [47] Endocrine sequelae of hematopoietic stem cell transplantation: Effects on mineral homeostasis and bone metabolism
    Miglietta, Francesca
    Iamartino, Luca
    Palmini, Gaia
    Giusti, Francesca
    Marini, Francesca
    Iantomasi, Teresa
    Brandi, Maria Luisa
    FRONTIERS IN ENDOCRINOLOGY, 2023, 13
  • [48] Mitochondrial calcium homeostasis in hematopoietic stem cell: Molecular regulation of quiescence, function, and differentiation
    Bonora, Massimo
    Kahsay, Asrat
    Pinton, Paolo
    INTER-ORGANELLAR CA2+ SIGNALING IN HEALTH AND DISEASE - PT A, 2021, 362 : 111 - 140
  • [49] Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis
    Chao Zhang
    Weiwei Yi
    Fei Li
    Xufei Du
    Hu Wang
    Ping Wu
    Chao Peng
    Man Luo
    Wen Hua
    Catherine CL Wong
    James J Lee
    Wen Li
    Zhihua Chen
    Songmin Ying
    Zhenyu Ju
    Huahao Shen
    Cell Research, 2018, 28 : 323 - 335
  • [50] Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner
    Kieslinger, Matthias
    Hiechinger, Silvia
    Dobreva, Gergana
    Consalez, G. Giacomo
    Grosschedl, Rudolf
    CELL STEM CELL, 2010, 7 (04) : 496 - 507
12345