The Mediator of Hematopoietic Stem Cell Homeostasis

被引：0
|
作者：
Borikar, Sneha [1 ]
Trowbridge, Jennifer J. [1 ]
机构：
[1] Jackson Lab Mammalian Genet, Bar Harbor, ME 04609 USA
来源：
Cell Stem Cell | 2016年 / 19卷 / 06期
关键词：
CHRONIC LYMPHOCYTIC-LEUKEMIA; MUTATIONS; MED12;
D O I：
10.1016/j.stem.2016.11.012
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Mechanisms establishing and maintaining promoter-enhancer interactions in hematopoietic stem cells (HSCs) to maintain stem cell identity are not fully understood. In this issue of Cell Stem Cell, Aranda-Orgilles et al. (2016) describe a role for a member of the Mediator complex in maintaining HSC-specific enhancers and hematopoietic homeostasis.
引用
收藏
页码：677 / 678
页数：2
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