Evaluation of a PCR-based universal heteroduplex generator assay as a tool for rapid detection of multidrug-resistant Mycobacterium tuberculosis in Peru

被引：11
|
作者：
Mayta, H
Gilman, RH
Arenas, F
Valencia, T
Caviedes, L
Montenegro, SH
Ticona, E
Ortiz, J
Chumpitaz, R
Evans, CA
Williams, DL
机构：
[1] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Internal Hlth, Baltimore, MD 21205 USA
[2] Univ Peruana Cayetano Heredia, Dept Microbiol, Lima, Peru
[3] Maria Auxiliadora Hosp, Lima, Peru
[4] Univ London Imperial Coll Sci Technol & Med, Dept Med, London, England
[5] Ochsner Med Fdnt, New Orleans, LA USA
[6] LSU SVM, Natl Hansens Dis Program, Lab Res Branch, Baton Rouge, LA USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 12期
关键词：
D O I：
10.1128/JCM.41.12.5774-5777.2003
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and reliability to detect and identify drug-resistant Mycobacterium tuberculosis in a developing country where tuberculosis is highly endemic.
引用
收藏
页码：5774 / 5777
页数：4
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