Studies with quinolines:: New synthetic routes to 4H,5H,6H,9H-benzo[ij]pyrano[2,3-b]quinolizine-8-one, 4H-pyrano[2,3-b]pyridine, 2H-pyran-2-one and pyranopyridoquinoline derivatives

被引：11
|
作者：
El-Taweel, FMAA [1 ]
机构：
[1] Fac Sci, Dept Chem, New Damietta, AR, Egypt
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 42卷 / 05期
关键词：
D O I：
10.1002/jhet.5570420529
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several new benzo[ij]pyrano[2,3-b]quinolizine-8-ones 5 and 4H-pyrano[2,3-b,jpyridine 8 derivatives were synthesized from 4-hydroxyquinolines 1. Reacting 3-acetyl-4-hydroxy-1-phenyl-1H-quinoline-2-one with dimethylformamide dimethylacetal afforded 3-(3-Dimethylamino-acryloyl)-4-hydroxy-1-phenyl-1H-quinolin-2-one 9. This reacted with hippuric acid and diethyl 3-oxoglutarate to give 2H-pyran-2-one 13 and pyranopyridoquinoline 17 respectively.
引用
收藏
页码：943 / 946
页数：4
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