An alternative approach to the synthesis of 5H-chromeno[4,3-b]pyridin-5-one system using the cleavage of 5H,9H-pyrano[2',3':5,6]chromeno[4,3-b]pyridine-5,9-diones with binucleophiles

被引：0
|
作者：
Oleg A. Lozinski
Tatyana V. Shokol
Roman I. Zubatyuk
Oleg V. Shishkin
Volodymir P. Khilya
机构：
[1] Kyiv National Taras Shevchenko University,Department of Inorganic Chemistry
[2] Division of Functional Materials Chemistry,undefined
[3] SSI “Institute for Single Crystals”,undefined
[4] National Academy of Science of Ukraine,undefined
[5] V. N. Karazin Kharkiv National University,undefined
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
carbonyl compounds; condensed chromones; isoxazoles; pyrazoles; cyclization; recyclization;
D O I：
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学科分类号：
摘要：
Hantzsch reaction has been successfully employed for a one-step assembling of pyranopyridine fragment to produce 5Н,9Н-pyrano[2',3':5,6]- chromeno[4,3-b]pyridine-5,9-diones which upon treatment with binucleophiles undergo chemoselective γ-pyrone ring opening with the concomitant recyclization to give five-membered cycles, providing a concise route to 6-pyrazolyl(isoxazolyl)-5H-chromeno[4,3-b]- pyridin-5-ones.
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页码：96 / 99
页数：3
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