New iboga-type alkaloids from Ervatamia officinalis and their anti-inflammatory activity

被引：3

作者：

Tang, Ben-qin ^{[1
]}

Li, Zi-wei ^{[2
]}

Li, Lin ^{[3
]}

Li, Bao-jing ^{[4
]}

Bian, Ya-qi ^{[3
]}

Yu, Guo-dong ^{[1
]}

Chang, Yu ^{[2
]}

Lee, Simon Ming-yuen ^{[3
]}

Zhang, Xiao-qi ^{[2
]}

机构：

[1] Shunde Polytech, Dept Med Sci, Foshan 528333, Peoples R China

[2] Jinan Univ, NMPA Key Lab Qual Evaluat TCM, Guangzhou 510632, Peoples R China

[3] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R China

[4] Yunnan Univ Chinese Med, Coll Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China

来源：

FITOTERAPIA | 2022年 / 156卷

基金：

中国国家自然科学基金;

关键词：

Ervatamia officinalis; Iboga-type alkaloids; Anti-inflammatory; Ervaoffines; NO release; MONOTERPENOID INDOLE ALKALOIDS;

D O I：

10.1016/j.fitote.2021.105085

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new iboga-type alkaloids, ervaoffines H-K (1-4), along with five known compounds were obtained from the aerial parts of Ervatamia officinalis. The absolute configurations of 1-4 were confirmed by X-ray diffraction and electronic circular dichroism (ECD) analyses. The isolates were tested for their anti-inflammatory activity. Compounds 1, 5, 6, and 9 showed potential inhibitory effect of NO production in LPS-stimulated BV2 and RAW264.7 cells.

引用

页数：7

共 50 条

[21] Anti-inflammatory Activity of Two New Indole Alkaloids from the Stems of Naucleaofficinalis
Chen, De-Li
Ma, Guo-Xu
He, Min-Jun
Liu, Yang-Yang
Wang, Xiao-Bing
Yang, Xin-Quan
HELVETICA CHIMICA ACTA, 2016, 99 (09) : 742 - 746
[22] Undescribed matrine-type alkaloids from Sophora alopecuroides with anti-inflammatory activity
Luo, Ding
Zou, Jia-Wen
Wang, Jing-Hao
Tian, He
Xie, Hua-Yan
Zhu, Tian-Xi
Zhu, Hui-Hui
Deng, Lu-Ming
Fan, Chun-Lin
Wang, Hao
Wang, Guo-Cai
Zhang, Yu-Bo
PHYTOCHEMISTRY, 2024, 218
[23] Iboga-type alkaloids with Indolizidino[8,7-b]Indole scaffold and bisindole alkaloids from Tabernaemontana bufalina Lour
Chen, Shun-Qing
Jia, Jia
Hu, Jing-Yao
Wu, Jun
Sun, Wen-Ting
Zheng, Mingxin
Wang, Xi
Zhu, Kong-Kai
Jiang, Cheng-Shi
Yang, Sheng-Ping
Zhang, Juan
Wang, Shou-Bao
Cai, You-Sheng
PHYTOCHEMISTRY, 2022, 196
[24] Hasubanan alkaloids with anti-inflammatory activity from Stephania longa
Liu, Hui
Liao, Wan-Qin
Lin, Rong-Xiao
Fan, Lixia
Sun, Jinyan
Chen, Hong-Yuan
Liu, Fang
Yang, An-Ping
NATURAL PRODUCT RESEARCH, 2022, 36 (11) : 2800 - 2805
[25] Anti-Inflammatory Activity of Diterpene Alkaloids from Aconitum baikalense
Yu. V. Nesterova
T. N. Povetieva
N. I. Suslov
G. N. Zyuz’kov
S. G. Aksinenko
S. V. Pushkarskii
A. V. Krapivin
Bulletin of Experimental Biology and Medicine, 2014, 156 : 665 - 668
[26] Quinotine alkaloids with anti-inflammatory activity from Zanthoxylum avicennae
Ji, Kai-Long
Liu, Wei
Yin, Wei-Hang
Li, Jing-Ya
Yue, Jian-Min
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 20 (20) : 4176 - 4182
[27] Diterpenoid Alkaloids from Delphinium ajacis and Their Anti-inflammatory Activity
Tang, Qing
Shen, Xi
Hao, Yi-Kun
Yang, Si-Yu
Fu, Jin-Tao
Wu, Tian-Yuan
Zhao, Hai-Yue
Qin, Baifu
Li, Yao-Lan
Zhang, Yu-Bo
Wang, Guo-Cai
CHEMISTRY & BIODIVERSITY, 2024, 21 (02)
[28] Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
Souto, Augusto Lopes
Tavares, Josean Fechine
da Silva, Marcelo Sobral
Formiga Melo Diniz, Margareth de Fatima
de Athayde-Filho, Petronio Filgueiras
Barbosa Filho, Jose Maria
MOLECULES, 2011, 16 (10): : 8515 - 8534
[29] Anti-Inflammatory Activity of Diterpene Alkaloids from Aconitum baikalense
Nesterova, Yu. V.
Povetieva, T. N.
Suslov, N. I.
Zyuz'kov, G. N.
Aksinenko, S. G.
Pushkarskii, S. V.
Krapivin, A. V.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2014, 156 (05) : 665 - 668
[30] Prenylated acetophenones from the roots of Calendula officinalis and their anti-inflammatory activity
Kadowaki, Wataru
Miyata, Ryo
Mizuno, Sayaka
Fujinami, Misa
Sato, Yoshizumi
Kumazawa, Shigenori
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2023, 87 (07) : 683 - 687

← 1 2 3 4 5 →