Analysis of IMPACT: is one blood eosinophil count measurement sufficient to predict ICS treatment response in COPD?

被引：2

作者：

Bafadhel, Mona ^{[1
]}

Barnes, Neil ^{[2
,3
]}

Bourke, Stephen ^{[4
,5
]}

Compton, Chris ^{[2
]}

Criner, Gerard ^{[6
]}

Dransfield, Mark ^{[7
]}

Halpin, David ^{[8
]}

Han, Meilan ^{[9
]}

Hartley, Benjamin ^{[10
]}

Jones, C. Elaine ^{[11
]}

Lange, Peter ^{[12
,13
]}

Lettis, Sally ^{[14
]}

Lipson, David ^{[15
,16
]}

Lomas, David ^{[17
]}

Martin, Neil ^{[2
,18
]}

Martinez, Fernando ^{[19
]}

Van der Valk, Ralf ^{[2
]}

Wise, Robert ^{[20
]}

Singh, David ^{[21
]}

机构：

[1] Univ Oxford, Nuffield Dept Med, Oxford, England

[2] GlaxoSmithKline, Brentford, England

[3] Barts & London Queen Marys Sch Med & Dent, London, England

[4] North Tyneside Gen Hosp, North Shields, England

[5] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England

[6] Temple Univ, Lewis Katz Sch Med, Philadelphia, PA 19122 USA

[7] Univ Alabama Birmingham, Lung Hlth Ctr, Div Pulm Allergy & Crit Care Med, Birmingham, AL USA

[8] Royal Devon & Exeter Hosp, Dept Resp Med, Exeter, Devon, England

[9] Univ Michigan, Pulm & Crit Care, Ann Arbor, MI 48109 USA

[10] Veramed Ltd, Twickenham, England

[11] GlaxoSmithKline, Res Triangle Pk, NC USA

[12] Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark

[13] Herlev & Gentofte Hosp, Dept Med, Herlev, Denmark

[14] GlaxoSmithKline, Uxbridge, Middx, England

[15] GlaxoSmithKline, Collegeville, PA USA

[16] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

[17] UCL, UCL Resp, London, England

[18] Univ Leicester, Leicester, Leics, England

[19] New York Presbyterian Weill Cornell Med Ctr, New York, NY USA

[20] Johns Hopkins Med, Div Pulm & Crit Care Med, Baltimore, MD USA

[21] Univ Manchester, Manchester, Lancs, England

来源：

EUROPEAN RESPIRATORY JOURNAL | 2019年 / 54卷

关键词：

D O I：

10.1183/13993003.congress-2019.OA260

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

OA260

引用

页数：3

共 47 条

[41] Early changes in eDiary COPD symptoms predict clinically relevant treatment response at 12 weeks: analysis from the CRYSTAL study (vol 15, pg 185, 2018)
Kostikas, K.
Aalamian-Mattheis, M.
Pagano, V
Nunez, X.
Fogel, R.
Patalano, F.
Clemens, A.
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2018, 15 (03) : 313 - 313
[42] Analysis of surrogate gene expression markers in peripheral blood of melanoma patients to predict response to adjuvant interferon treatment (EORTC 18991 SIDE STUDY)
Busse, A.
Rapion, J.
Fusi, A.
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Nonnenmacher, A.
Santinami, M.
Kruit, W. H.
Testori, A.
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Dalgleish, A. G.
Spatz, A.
Eggermont, A. M.
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ONKOLOGIE, 2012, 35 : 192 - 193
[43] Impact of Estimated Pulse Wave Velocity and Its Response to Treatment on Survival: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial
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CIRCULATION, 2019, 140
[44] Nadir/pre-chemoradiotherapy ratio of white blood-cell count can predict tumor response and recurrence-free survival in locally advanced rectal cancer: a multi-institutional analysis
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Taek Keun Nam
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[45] Nadir/pre-chemoradiotherapy ratio of white blood-cell count can predict tumor response and recurrence-free survival in locally advanced rectal cancer: a multi-institutional analysis
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Nam, Taek Keun
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INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2019, 34 (01) : 105 - 112
[46] Impact of CD4+blood cell count and HIV viral load on treatment response with direct acting antivirals in HIV and HCV coinfected patients: insights from the German Hepatitis C-Registry
Bischoff, Jenny
Mauss, Stefan
Cordes, Christiane
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Manns, Michael P.
Baumgarten, Axel
Rockstroh, Juergen K.
HIV CLINICAL TRIALS, 2018, 19 (06): : 225 - 234
[47] Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial (vol 7, pg 745, 2019)
Pascoe, S.
Barnes, N.
Brusselle, G.
LANCET RESPIRATORY MEDICINE, 2021, 9 (12): : E114 - E114

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