Analysis of IMPACT: is one blood eosinophil count measurement sufficient to predict ICS treatment response in COPD?

被引：2

作者：

Bafadhel, Mona ^{[1
]}

Barnes, Neil ^{[2
,3
]}

Bourke, Stephen ^{[4
,5
]}

Compton, Chris ^{[2
]}

Criner, Gerard ^{[6
]}

Dransfield, Mark ^{[7
]}

Halpin, David ^{[8
]}

Han, Meilan ^{[9
]}

Hartley, Benjamin ^{[10
]}

Jones, C. Elaine ^{[11
]}

Lange, Peter ^{[12
,13
]}

Lettis, Sally ^{[14
]}

Lipson, David ^{[15
,16
]}

Lomas, David ^{[17
]}

Martin, Neil ^{[2
,18
]}

Martinez, Fernando ^{[19
]}

Van der Valk, Ralf ^{[2
]}

Wise, Robert ^{[20
]}

Singh, David ^{[21
]}

机构：

[1] Univ Oxford, Nuffield Dept Med, Oxford, England

[2] GlaxoSmithKline, Brentford, England

[3] Barts & London Queen Marys Sch Med & Dent, London, England

[4] North Tyneside Gen Hosp, North Shields, England

[5] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England

[6] Temple Univ, Lewis Katz Sch Med, Philadelphia, PA 19122 USA

[7] Univ Alabama Birmingham, Lung Hlth Ctr, Div Pulm Allergy & Crit Care Med, Birmingham, AL USA

[8] Royal Devon & Exeter Hosp, Dept Resp Med, Exeter, Devon, England

[9] Univ Michigan, Pulm & Crit Care, Ann Arbor, MI 48109 USA

[10] Veramed Ltd, Twickenham, England

[11] GlaxoSmithKline, Res Triangle Pk, NC USA

[12] Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark

[13] Herlev & Gentofte Hosp, Dept Med, Herlev, Denmark

[14] GlaxoSmithKline, Uxbridge, Middx, England

[15] GlaxoSmithKline, Collegeville, PA USA

[16] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

[17] UCL, UCL Resp, London, England

[18] Univ Leicester, Leicester, Leics, England

[19] New York Presbyterian Weill Cornell Med Ctr, New York, NY USA

[20] Johns Hopkins Med, Div Pulm & Crit Care Med, Baltimore, MD USA

[21] Univ Manchester, Manchester, Lancs, England

来源：

EUROPEAN RESPIRATORY JOURNAL | 2019年 / 54卷

关键词：

D O I：

10.1183/13993003.congress-2019.OA260

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

OA260

引用

页数：3

共 47 条

[1] A single blood eosinophil count measurement is as good as two for prediction of ICS treatment response in the IMPACT trial
Bafadhel, Mona
Barnes, Neil
Bourke, Stephen C.
Compton, Chris
Criner, Gerard J.
Dransfield, Mark T.
Halpin, David M. G.
Han, MeiLan K.
Hartley, Benjamin
Jones, C. Elaine
Lange, Peter
Lettis, Sally
Lipson, David A.
Lomas, David A.
Martin, Neil
Martinez, Fernando J.
Wise, Robert
Singh, Dave
EUROPEAN RESPIRATORY JOURNAL, 2021, 58 (03)
[2] Eosinophil Count As A Predictor Of Response To Inhaled Corticosteroids (ics) In COPD
Barnes, N.
Pavord, I.
Jones, P. W.
Wedzicha, J. A.
Lettis, S.
Locantore, N.
Pascoe, S.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
[3] Blood eosinophil count (BEC) measured before starting inhaled corticosteroids (ICS) is better associated with treatment response to ICS in COPD.
Mathioudakis, Alexander
Bate, Sebastian
Sivapalan, Pradeesh
Jensen, Jens-Ulrik
Singh, Dave
Vestbo, Jorgen
EUROPEAN RESPIRATORY JOURNAL, 2023, 62
[4] Blood eosinophil count to predict bronchial eosinophilic inflammation in COPD
Schleich, Florence
Corhay, Jean-Louis
Louis, Renaud
EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (05) : 1562 - 1564
[5] Blood eosinophil count and GOLD stage predict response to maintenance azithromycin treatment in COPD patients with frequent exacerbations
Djamin, Remco S.
Bafadhel, Mona
Uzun, Sevim
Russell, Richard E. K.
Ermens, Anton A. M.
Kerstens, Rene
Aerts, Joachim G. J. V.
Pavord, Ian D.
van der Eerden, Menno M.
RESPIRATORY MEDICINE, 2019, 154 : 27 - 33
[6] Blood eosinophil count predicts treatment failure and hospital readmission for COPD
Kerkhof, Marjan
Chaudhry, Isha
Pavord, Ian D.
Miravitlles, Marc
Rhee, Chin Kook
Halpin, David M. G.
Usmani, Omar S.
Jones, Rupert
Kocks, Janwillem
Alacqua, Marianna
Morris, Tamsin
Kaplan, Alan
Price, David B.
ERJ OPEN RESEARCH, 2020, 6 (04) : 1 - 12
[7] Minimal effect of inhaled corticosteroids (ICS) on blood eosinophil count in steroid-naive COPD patients
Kreindler, James
Locantore, Nicholas
Watkins, Michael
Lettis, Sally
Tal-Singer, Ruth
EUROPEAN RESPIRATORY JOURNAL, 2015, 46
[8] Late Breaking Abstract - Blood eosinophil counts and treatment response in COPD: analyses of IMPACT
Pascoe, Steven
Barnes, Neil
Brusselle, Guy
Compton, Chris
Criner, Gerard
Dransfield, Mark
Halpin, David M. G.
Han, Meilan K.
Hartley, Benjamin
Hilton, Emma
Lange, Peter
Lettis, Sally
Lipson, David A.
Lomas, David
Martinez, Fernando J.
Papi, Alberto
Roche, Nicolas
Van der Valk, Ralf J. P.
Wise, Robert
Singh, Dave
EUROPEAN RESPIRATORY JOURNAL, 2018, 52
[9] Blood Eosinophil Count To Predict Bronchial Eosinophilic Inflammation In Chronic Obstructive Pulmonary Disease (COPD)
Schleich, F. N.
Corhay, J. -L.
Louis, R.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
[10] Impact of blood eosinophil count on clinical outcomes in hospitalized Syrian patients with COPD exacerbation
Albuaini, Sara
Najjar, Michel
Tulaiba, Dania
Al Bardan, Hussam
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2024, 52 (11)

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