Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5

被引：15
|
作者：
Shalekoff, S
Tiemessen, CT
机构：
[1] Univ Witwatersrand, Dept Virol, ZA-2050 Witwatersrand, South Africa
[2] Natl Inst Virol, AIDS Virus Res Unit, Johannesburg, South Africa
来源：
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2001年 / 8卷 / 02期
关键词：
D O I：
10.1128/CDLI.8.2.432-436.2001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Expression of the chemokine receptors CXCR4 and CCR5 was monitored using EDTA-anticoagulated whole blood held for different time periods prior to fluorescent-antibody staining. When left overnight CXCR4 expression on leukocytes was substantially increased, whereas CCR5 expression was reduced. The results were similar when heparin and acid-citrate-dextrose were used as anticoagulants.
引用
收藏
页码：432 / 436
页数：5
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