Retrieval and Investigation of Data on SARS-CoV-2 and COVID-19 Using Bioinformatics Approach

被引:22
|
作者
Fahmi, Muhamad [1 ,2 ]
Kharisma, Viol Dhea [3 ,4 ,5 ]
Ansori, Arif Nur Muhammad [6 ,7 ]
Ito, Masahiro [1 ,2 ]
机构
[1] Ritsumeikan Univ, Grad Sch Life Sci, Adv Life Sci Program, Shiga, Japan
[2] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Kusatsu, Japan
[3] Brawijaya Univ, Fac Mathemat & Nat Sci, Dept Biol, Master Program Biol, Malang, Indonesia
[4] Generasi Biol Indonesia GENBINESIA Fdn, Div Mol Biol & Genet, Computat Virol & Complex Sci Res Unit, Gresik, Indonesia
[5] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Malang, Indonesia
[6] Airlangga Univ, Fac Vet Med, Doctoral Program Vet Sci, Kampus C Univ Airlangga, Surabaya, Indonesia
[7] Universal Sci Educ & Res Network USERN, Systemat Review & Metaanal Expert Grp SRMEG, Surabaya, Indonesia
来源
关键词
COVID-19; Databases; Information hubs; Molecular evolution; Phylogenetic inference; SARS-CoV-2; Vaccine design; MULTIPLE SEQUENCE ALIGNMENT; HEPATITIS-C VIRUS; B-CELL EPITOPES; DATA-BANK PDB; HLA-DR; CORONAVIRUS; PREDICTION; PROTEIN; RECOMBINATION; MECHANISMS;
D O I
10.1007/978-3-030-63761-3_47
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Sudden emergence and a rapid outbreak of SARS-CoV-2 accompanied by a devastating impact on the economy and public health has driven extensive scientific mobilization to study and elucidate the various associated concerns about SARS-CoV-2. Bioinformatics plays a crucial role in addressing and providing solutions to questions about SARS-CoV-2. It helps shorten the duration for the vaccine development process and the discovery of potential clinical interventions through the simulation and information retrieval, and the development of well-ordered information hubs and resources, which are essential to derive data and meaningful findings from the current massive information about SARS-CoV-2. Advanced algorithms in this field also provide approaches that are essential to elucidate the relationship, origin, and evolutionary process of SARS-CoV-2. Here, we report essential bioinformatics entities, such as database and platform development, molecular evolution and phylogenetic analyses, and vaccine designs, that are useful to solve the SARS-CoV-2 conundrum.
引用
收藏
页码:839 / 857
页数:19
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