Bhlhe40: Gatekeeper of the GC

被引：1

作者：

Nutt, Stephen L. ^{[1
,2
]}

Tellier, Julie ^{[1
,2
]}

机构：

[1] Walter & Eliza Hall Inst Med Res, Parkville, Vic, Australia

[2] Univ Melbourne, Dept Med Biol, Parkville, Vic, Australia

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2021年 / 219卷 / 02期

关键词：

D O I：

10.1084/jem.20212333

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The generation of high-affinity antibodies in the germinal center (GC) requires interplay between GC B cells and T follicular helper cells. Rauschmeier et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20211406) report that Bhlhe40 restrains GC output through distinct regulatory roles in both arms of the response.

引用

页数：3

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