Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization

被引：11
|
作者：
Aventín, A
La Starza, R
Martínez, C
Wlodarska, I
Boogaerts, M
Van den Berghe, H
Mecucci, C
机构：
[1] Univ Perugia, Inst Hematol, Monteluce Policlin, I-06100 Perugia, Italy
[2] Univ Barcelona, Hosp St Pau, Dept Hematol, Barcelona, Spain
[3] Univ Leuven, Dept Hematol, Louvain, Belgium
[4] Univ Leuven, Ctr Human Genet, Louvain, Belgium
来源：
CANCER GENETICS AND CYTOGENETICS | 1999年 / 108卷 / 01期
关键词：
D O I：
10.1016/S0165-4608(98)00110-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We describe two cases of acute myeloblastic leukemia, classified as M4 and M5 in the French-American-British nomenclature, with an 11q23 rearrangement at karyotypic analysis. The involvement of the MLL gene with two new partner loci on chromosome 10q22 and 8q24, respectively, was demonstrated by fluorescence in situ hybridization using a YAC clone B22B2L. (C) Elsevier Science Inc., 1998.
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收藏
页码：48 / 52
页数：5
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