Involvement of MLL gene in a t(10;11)(q22;q23) and a t(8;11)(q24;q23) identified by fluorescence in situ hybridization

被引：11
|
作者：
Aventín, A
La Starza, R
Martínez, C
Wlodarska, I
Boogaerts, M
Van den Berghe, H
Mecucci, C
机构：
[1] Univ Perugia, Inst Hematol, Monteluce Policlin, I-06100 Perugia, Italy
[2] Univ Barcelona, Hosp St Pau, Dept Hematol, Barcelona, Spain
[3] Univ Leuven, Dept Hematol, Louvain, Belgium
[4] Univ Leuven, Ctr Human Genet, Louvain, Belgium
来源：
CANCER GENETICS AND CYTOGENETICS | 1999年 / 108卷 / 01期
关键词：
D O I：
10.1016/S0165-4608(98)00110-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We describe two cases of acute myeloblastic leukemia, classified as M4 and M5 in the French-American-British nomenclature, with an 11q23 rearrangement at karyotypic analysis. The involvement of the MLL gene with two new partner loci on chromosome 10q22 and 8q24, respectively, was demonstrated by fluorescence in situ hybridization using a YAC clone B22B2L. (C) Elsevier Science Inc., 1998.
引用
收藏
页码：48 / 52
页数：5
相关论文
共 50 条
  • [31] t(11;14)(q23;q24) generates an MLL-human gephyrin fusion gene along with a de facto truncated MLL in acute monoblastic leukemia
    Kuwada, N
    Kimura, F
    Matsumura, T
    Yamashita, T
    Nakamura, Y
    Wakimoto, N
    Ikeda, T
    Sato, K
    Motoyoshi, K
    CANCER RESEARCH, 2001, 61 (06) : 2665 - 2669
  • [32] Involvement of the MLL and RARα genes in a patient with acute monocytic leukemia with t(11;17)(q23;q12)
    S Shekhter-Levin
    SM Gollin
    SS Kaplan
    RL Redner
    Leukemia, 2000, 14 : 520 - 522
  • [33] Parental origins and segregation outcomes involving the t(11;22)(q23;q11.2)
    Leve, M
    Paniagua, R
    Moore, JW
    CYTOGENETIC AND GENOME RESEARCH, 2004, 106 (01) : 131 - 131
  • [34] The Constitutional Balanced Translocation t(11;22)(q23;q11.2)-An Indian Account
    Kamath, Vandana
    Srivastava, Vivi M.
    Yuvarani, S.
    Chacko, Mary Purna
    Bhattacharya, Saurabh Kumar
    Oommen, Samuel Phillip
    Danda, Sumita
    Korula, George
    JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2019, 13 (01) : GC1 - GC4
  • [35] Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14)
    Kuefer, MU
    Chinwalla, V
    Zeleznik-Le, NJ
    Behm, FG
    Naeve, CW
    Rakestraw, KM
    Mukatira, ST
    Raimondi, SC
    Morris, SW
    ONCOGENE, 2003, 22 (09) : 1418 - 1424
  • [36] Translocation t(11;19)(q23;q13.1) without MLL Rearrangement in Acute Myeloid Leukemia: Heterogeneity of the 11q23 Breakpoints
    Yamamoto, Katsuya
    Kawamoto, Shinichiro
    Kakiuchi, Seiji
    Yakushijin, Kimikazu
    Matsuoka, Hiroshi
    Minami, Hironobu
    ACTA HAEMATOLOGICA, 2015, 134 (02) : 76 - 79
  • [37] A novel case of acute lymphoblastic leukemia with t(1;4;6;11)(q31;q27;q22;q23)
    Patel, Dharmesh M.
    Patel, Girish H.
    Brahmbhatt, Manisha M.
    Trivedi, Pina J.
    Shukla, Shilin N.
    Patel, Prabhudas S.
    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2012, 34 (06) : E9 - E11
  • [38] Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14)
    Martin U Kuefer
    Vandana Chinwalla
    Nancy J Zeleznik-Le
    Frederick G Behm
    Clayton W Naeve
    Karen M Rakestraw
    Suraj T Mukatira
    Susana C Raimondi
    Stephan W Morris
    Oncogene, 2003, 22 : 1418 - 1424
  • [39] High incidence of familial breast cancer segregates with constitutional t(11;22)(q23;q11)
    Wieland, Ilse
    Muschke, Petra
    Volleth, Marianne
    Roepke, Albrecht
    Pelz, Antje-Friederike
    Stumm, Markus
    Wieacker, Peter
    GENES CHROMOSOMES & CANCER, 2006, 45 (10): : 945 - 949
  • [40] The evolution of karyotype in children with t(4;11)(q21;q23)
    Pastwinska, A.
    Chmarzynska-Mroz, E.
    Stefaniak, A.
    Pawelec, K.
    Wasiutynski, A.
    Matysiak, M.
    Pienkowska-Grela, B.
    CHROMOSOME RESEARCH, 2009, 17 : 121 - 122
12345