Relationship between serum butyrylcholinesterase and obesity in dogs A preliminary report

The aim of this study was to analyse serum butyrylcholinesterase (BChE) values in experimentally developed obesity in Beagle dogs A short-term fattening protocol was applied to 11 dogs to obtain a wide range of bodyweight (BW) gains and body condition scores (BCS) of 4 and 5 four other dogs with BCS scores of 3 were used as controls A significant Increase in serum BChE activity in overweight dogs was observed when compared with the group of optimal weight dogs Significant correlation was detected between BChE and BCS (r = 0 911) BW (r = 0 538) and morphological parameters (waist and thorax circumference r = 0 563 and r = 0 552 respectively) Serum BChE concentration had a negative correlation with adiponectin concentration (r = 0 719) and a positive correlation with serum lipid profile (cholesterol (r = 0 781) HDL-cholesterol (r = 0 763) LDL-cholesterol (r = 0 878)) It was concluded that serum BChE activity is Increased in experimentally overweight dogs and is correlated with other physical and biochemical markers of obesity (c) 2009 Elsevier Ltd All rights reserved