Serum butyrylcholinesterase activity in dogs with diabetes mellitus

被引：6

作者：

Tvarijonaviciute, A. ^{[2
]}

Ceron, J. J. ^{[2
]}

Caldin, M. ^{[1
]}

机构：

[1] San Marco Vet Hosp, Padua, Italy

[2] Univ Murcia, Sch Vet, Dept Anim Med & Surg, E-30100 Murcia, Spain

来源：

VETERINARY JOURNAL | 2012年 / 192卷 / 03期

关键词：

Butyrylcholinesterase (BChE); Diabetes mellitus; Dog; Triglycerides; CHOLINESTERASE ACTIVITY; RISK-FACTORS; OBESITY; BASE;

D O I：

10.1016/j.tvjl.2011.06.040

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Increased serum butyrylcholinesterase (BChE) activity is a feature of diabetes mellitus (DM) in humans and rats. The objective of this study was to evaluate serum BChE activity in diabetic dogs. The activity of the enzyme was assessed in three cohorts of animals: (1) dogs with naturally occurring DM (n = 74); (2) clinically normal dogs (n = 74); and (3) dogs with various other diseases (n = 74). A statistically significant increase in BChE activity was found in the diabetic dogs (7.59 +/- 2.9 kUI/L) compared with the clinically normal animals (6.12 +/- 1.94 kUI/L; P < 0.05), and with the dogs with other diseases (5.55 +/- 2.06 kUI/L; P < 0.01). Such increased activity could be the result of the altered glucose and lipid metabolism that occurs in DM. (C) 2012 Published by Elsevier Ltd.

引用

页码：494 / 497

页数：4

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