Nuclear Architecture: Past and Future Tense

被引:6
|
作者
Gasser, Susan M. [1 ,2 ]
机构
[1] Friedrich Miescher Inst Biomed Res, Maulbeerstr 66, CH-4058 Basel, Switzerland
[2] Univ Basel, Fac Nat Sci, CH-4056 Basel, Switzerland
关键词
TOPOISOMERASE-II; CHROMATIN; YEAST; CHROMOSOMES; ATTACHMENT; PROTEINS; DOMAINS; RAP1;
D O I
10.1016/j.tcb.2016.04.011
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The architecture of the interphase nucleus remains a treasure trove for explorers of the 3D folding of macromolecules, like DNA, and of their related functions. Only recently has there been insight into how transient interactions of the genome and its associated proteins, in space and time, facilitate transcription, replication, and repair.
引用
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页码:473 / 475
页数:3
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