Cobalt-Catalyzed Diastereoselective and Enantioselective Hydrosilylation of Achiral Cyclopropenes

被引：30
|
作者：
Dian, Longyang [1 ]
Marek, Ilan [1 ]
机构：
[1] Technion Israel Inst Technol, Schulich Fac Chem, IL-3200009 Haifa, Israel
来源：
ORGANIC LETTERS | 2020年 / 22卷 / 12期
基金：
以色列科学基金会;
关键词：
SIMMONS-SMITH REACTION; DOMINO REACTIONS; CYCLOPROPANATION; HYDROBORATION; AMINOCYCLOPROPANES; CARBOMAGNESIATION; ALCOHOLS; ACCESS;
D O I：
10.1021/acs.orglett.0c01833
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A mild diastereoselective and enantioselective cobalt-catalyzed hydrosilylation reaction of achiral cyclopropenes has been developed. In this protocol, various substituted cyclopropenes and arylsilanes were transformed, in the presence of readily available chiral cobalt complex, into silylcyclopropanes with high selectivities.
引用
收藏
页码：4914 / 4918
页数：5
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