Cobalt-Catalyzed Diastereoselective and Enantioselective Hydrosilylation of Achiral Cyclopropenes

被引：30
|
作者：
Dian, Longyang [1 ]
Marek, Ilan [1 ]
机构：
[1] Technion Israel Inst Technol, Schulich Fac Chem, IL-3200009 Haifa, Israel
来源：
ORGANIC LETTERS | 2020年 / 22卷 / 12期
基金：
以色列科学基金会;
关键词：
SIMMONS-SMITH REACTION; DOMINO REACTIONS; CYCLOPROPANATION; HYDROBORATION; AMINOCYCLOPROPANES; CARBOMAGNESIATION; ALCOHOLS; ACCESS;
D O I：
10.1021/acs.orglett.0c01833
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A mild diastereoselective and enantioselective cobalt-catalyzed hydrosilylation reaction of achiral cyclopropenes has been developed. In this protocol, various substituted cyclopropenes and arylsilanes were transformed, in the presence of readily available chiral cobalt complex, into silylcyclopropanes with high selectivities.
引用
收藏
页码：4914 / 4918
页数：5
相关论文
共 50 条
  • [31] Highly Enantioselective Cobalt-Catalyzed Hydroboration of Diaryl Ketones
    Liu, Wenbo
    Guo, Jun
    Xing, Shipei
    Lu, Zhan
    ORGANIC LETTERS, 2020, 22 (07) : 2532 - 2536
  • [32] Cobalt-Catalyzed Enantioselective Vinylation of Activated Ketones and Imines
    Huang, Yuan
    Huang, Rui-Zhi
    Zhao, Yu
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (20) : 6571 - 6576
  • [33] Cobalt-Catalyzed Enantioselective Intramolecular Hydroacylation of Ketones and Olefins
    Yang, Junfeng
    Yoshikai, Naohiko
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (48) : 16748 - 16751
  • [34] Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination
    Ghorai, Samir
    Chirke, Sahadev Shrihari
    Xu, Wen-Bin
    Chen, Jia-Feng
    Li, Changkun
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (29) : 11430 - 11434
  • [35] Cobalt-Catalyzed Enantioselective Reductive Amination of Ketones with Hydrazides
    Chen, Tiantian
    Hu, Yanhua
    Tang, Xuyang
    Zou, Yashi
    Wei, Liangming
    Zhang, Zhenfeng
    Zhang, Wanbin
    ORGANIC LETTERS, 2023, 26 (04) : 769 - 774
  • [36] Cobalt-Catalyzed Diastereoselective Difluoroalkylation/Giese Addition Domino Reactions
    Han, Shengnan
    Liu, Shaodong
    Liu, Lei
    Ackermann, Lutz
    Li, Jie
    ORGANIC LETTERS, 2019, 21 (14) : 5387 - 5391
  • [37] Diastereoselective and enantioselective cyclopropanation of alkenes catalyzed by cobalt porphyrins
    Huang, LY
    Chen, Y
    Gao, GY
    Zhang, XP
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (21): : 8179 - 8184
  • [38] Regio-controllable Cobalt-Catalyzed Sequential Hydrosilylation/Hydroboration of Arylacetylenes
    Cheng, Zhaoyang
    Guo, Jun
    Sun, Yufeng
    Zheng, Yushan
    Zhou, Zhehong
    Lu, Zhan
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (41) : 22454 - 22460
  • [39] Cobalt-Catalyzed Regio-, Diastereo- and Enantioselective Intermolecular Hydrosilylation of 1,3-Dienes with Prochiral Silanes
    Wang, Lei
    Lu, Wenxin
    Zhang, Jiwu
    Chong, Qinglei
    Meng, Fanke
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 61 (30)
  • [40] Cobalt-Catalyzed Chemoselective and Divergent Synthesis of Vinylsilanes through Hydrosilylation of Acetylene
    Long, Xianyang
    Zhu, Dong
    Zhu, Shifa
    ACS CATALYSIS, 2025, 15 (06): : 4429 - 4440
12345