共 50 条
Cytotoxic activity against prelabelled RTG-2 cells in the turbot, Scophthalmus maximus (L.)
被引:0
|作者:
Tafalla, C
[1
]
Figueras, A
[1
]
Novoa, B
[1
]
机构:
[1] CSIC, Inst Invest Marinas, Vigo 36208, Spain
关键词:
turbot;
leucocytes;
cytotoxicity;
fish;
non-specific natural cytotoxic cells;
immune system;
D O I:
暂无
中图分类号:
S9 [水产、渔业];
学科分类号:
0908 ;
摘要:
Leucocytes derived from head kidney, blood and spleen of turbot, Scophthalmus maximus (L.), exhibited cytotoxic activities against an established cell line (RTG-2) derived from rainbow trout, Oncorhynchus mykiss (Walbaum). The optimal effector:target ratio, temperature and incubation period for the activity was determined. Cytotoxicity was not caused by released factors, as effector:target contact was needed. Visualization of the cultures under the transmission electron microscope corroborated the contact between leucocytes and target cells and suggested the implication of monocyte-like cells in this cell-mediated cytotoxicity.
引用
收藏
页码:169 / 175
页数:7
相关论文