Walsucochins A and B with an unprecedented skeleton isolated from Walsura cochinchinensis

被引：38

作者：

Zhou, Zhi-Wang ^{[1
]}

Yin, Sheng ^{[1
]}

Zhang, Hai-Yan ^{[1
]}

Fu, Yan ^{[1
]}

Yang, Sheng-Ping ^{[1
]}

Wang, Xiao-Ning ^{[1
]}

Wu, Yan ^{[1
]}

Tang, Xi-Can ^{[1
]}

Yue, Jian-Min ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Shanghai 201203, Peoples R China

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 03期

关键词：

D O I：

10.1021/ol702831e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Walsucochins A (1) and B (2) with an unprecedented skeleton were isolated from Walsura cochinchinensis. Their structures including absolute configuration were elucidated by spectral methods. A biosynthetic pathway of 1 and 2 was postulated. Both 1 and 2 exhibited significant cell protecting activities against H2O2-induced PC12 cell damage.

引用

页码：465 / 468

页数：4

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