Walsucochins A and B with an unprecedented skeleton isolated from Walsura cochinchinensis

被引：38
|
作者：
Zhou, Zhi-Wang [1 ]
Yin, Sheng [1 ]
Zhang, Hai-Yan [1 ]
Fu, Yan [1 ]
Yang, Sheng-Ping [1 ]
Wang, Xiao-Ning [1 ]
Wu, Yan [1 ]
Tang, Xi-Can [1 ]
Yue, Jian-Min [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Shanghai 201203, Peoples R China
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 03期
关键词：
D O I：
10.1021/ol702831e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Walsucochins A (1) and B (2) with an unprecedented skeleton were isolated from Walsura cochinchinensis. Their structures including absolute configuration were elucidated by spectral methods. A biosynthetic pathway of 1 and 2 was postulated. Both 1 and 2 exhibited significant cell protecting activities against H2O2-induced PC12 cell damage.
引用
收藏
页码：465 / 468
页数：4
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