Efficient synthesis of substituted biaryl anilines and biaryl phenols via a Suzuki cross-coupling reaction

被引:23
|
作者
Liu, B [1 ]
Moffett, KK [1 ]
Joseph, RW [1 ]
Dorsey, BD [1 ]
机构
[1] Locus Pharmaceut Inc, Blue Bell, PA 19422 USA
关键词
Suzuki coupling; Pd catalyst; biaryl building blocks;
D O I
10.1016/j.tetlet.2005.01.125
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient synthesis of biaryl building blocks with multiple point diversities via a Suzuki cross-coupling reaction using a commercially available preformed Pd catalyst 1 was reported. Substituted biaryl anilines and phenols were obtained in one step from commercially available aryl halides. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1779 / 1782
页数:4
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