A rapid and high-throughput quantum dots bioassay for monitoring of perfluorooctane sulfonate in environmental water samples

被引：34
|
作者：
Zhang, Jiong [1 ]
Wan, Yanjian [1 ]
Li, Yuanyuan [1 ]
Zhang, Qiongfang [1 ]
Xu, Shunqing [1 ]
Zhu, Huijun [2 ]
Shu, Baihua [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Key Lab Environm & Hlth,Minist Educ, Wuhan 430030, Hubei Province, Peoples R China
[2] Cranfield Univ, Kempston MK43 0AL, Beds, England
来源：
ENVIRONMENTAL POLLUTION | 2011年 / 159卷 / 05期
基金：
中国国家自然科学基金; 国家高技术研究发展计划(863计划);
关键词：
High-throughput; Monitoring; Quantum dots bioassay; Perfluorooctane sulfonate; PERFLUORINATED COMPOUNDS; REVERSE-OSMOSIS; WASTE-WATER; HUMAN BLOOD; CHINA; PFOS; FLUOROCHEMICALS; NANOPARTICLES; MEMBRANES; BINDING;
D O I：
10.1016/j.envpol.2011.01.011
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Currently HPLC/MS is the state of the art tool for environmental/drinking water perfluorooctane sulfonate (PFOS) monitoring. PFOS can bind to peroxisomal proliferator-activated receptor-alpha (PPAR alpha), which forms heterodimers with retinoid X receptors (RXRs) and binds to PPAR response elements. In this bioassay free PFOS in water samples competes with immobilized PFOS in ELISA plates for a given amount of PPAR alpha-RXR alpha. It can be determined indirectly by immobilizing PPAR alpha-RXR alpha-PFOS complex to another plate coated with PPAR alpha antibody and subsequent measuring the level of PPAR alpha-RXR alpha by using biotin-modified PPAR alpha-RXR alpha probes-quantum dots-streptavidin detection system. The rapid and high-throughput bioassay demonstrated a detection limit of 2.5 ng L(-1) with linear range between 2.5 ng L(-1) and 75 ng L(-1). Detection results of environmental water samples were highly consistent between the bioassay and HPLC/MS. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1348 / 1353
页数：6
相关论文
共 50 条
  • [21] Graphene Quantum Dots Sensor for the Determination of Graphene Oxide in Environmental Water Samples
    Benitez-Martinez, Sandra
    Inmaculada Lopez-Lorente, Angela
    Valcarcel, Miguel
    ANALYTICAL CHEMISTRY, 2014, 86 (24) : 12279 - 12284
  • [22] High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples
    Wang, Jing
    Liu, Qian
    Gao, Yan
    Wang, Yawei
    Guo, Liangqia
    Jiang, Guibin
    ANALYTICAL CHEMISTRY, 2015, 87 (13) : 6931 - 6936
  • [23] Novel high-throughput bioassays for endocrine disrupting compounds in complex water samples
    Aldred, Shelley Force
    Snyder, Shane A.
    Clarke, Bradley O.
    Trinklein, Nathan D.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [24] BIOCONJUGATED QUANTUM DOTS BASED RAPID DETECTION OF PATHOGENIC BACTERIA FROM WATER SAMPLES
    Jackeray, Richa
    Singht, Gurpal
    Jain, Swati
    Ckv, Zainul Abid
    Singht, Harpal
    Zaidi, Neelam H.
    Soni, Udit
    Sapra, Sameer
    Shrivastav, T. G.
    INTERNATIONAL JOURNAL OF NANOSCIENCE, 2011, 10 (1-2) : 199 - 203
  • [25] Rapid and high-throughput determination of cationic surfactants in environmental water samples by automated on-line polymer monolith microextraction coupled to high performance liquid chromatography-mass spectrometry
    Peng, Xi-Tian
    Shi, Zhi-Guo
    Feng, Yu-Qi
    JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (23) : 3588 - 3594
  • [26] High-Throughput Measurement of the Long Excited-state Lifetime of Quantum Dots in Flow Cytometry
    Dahal, Eshan
    Cao, Ruofan
    Jenkins, Patrick
    Houston, Jessica P.
    IMAGING, MANIPULATION, AND ANALYSIS OF BIOMOLECULES, CELLS, AND TISSUES XII, 2014, 8947
  • [27] A High-Throughput Microfluidic Magnetic Separation (μFMS) Platform for Water Quality Monitoring
    Castillo-Torres, Keisha Y.
    McLamore, Eric S.
    Arnold, David P.
    MICROMACHINES, 2020, 11 (01)
  • [28] A high-throughput headspace gas chromatographic technique for the determination of nitrite content in water samples
    Zhang, Shu-Xin
    Peng, Rong
    Jiang, Ran
    Chai, Xin-Sheng
    Barnes, Donald G.
    JOURNAL OF CHROMATOGRAPHY A, 2018, 1538 : 104 - 107
  • [29] Use of an immunomagnetic separation-fluorescent immunoassay (IMS-FIA) for rapid and high throughput analysis of environmental water samples
    Yu, H
    ANALYTICA CHIMICA ACTA, 1998, 376 (01) : 77 - 81
  • [30] High-Throughput Sequencing Enables Rapid Analyses of Nematode Mitochondrial Genomes from an Environmental Sample
    Jain, Akshita
    Li, Tongda
    Wainer, John
    Edwards, Jacqueline
    Rodoni, Brendan C.
    Sawbridge, Timothy I.
    PATHOGENS, 2025, 14 (03):
12345