Blood group does not appear to affect longevity a pilot study in centenarians from Western Sicily

被引：6

作者：

Vasto, Sonya ^{[1
,2
,3
]}

Caruso, Calogero ^{[2
,3
]}

Castiglia, Laura ^{[2
,3
]}

Duro, Giovanni ^{[5
]}

Monastero, Roberto ^{[4
]}

Rizzo, Claudia ^{[2
,3
]}

机构：

[1] AOUP PAOLO GIACCONE, UO Immunoematol & Med Trasfus, I-90127 Palermo, PA, Italy

[2] Univ Med Sch Paolo Giaccone Hosp, Immunohaemathol Unit, Palermo, PA, Italy

[3] Univ Palermo, Dept Pathobiol Med & Forens Biotechnol, Palermo, PA, Italy

[4] Univ Palermo, Dept Expt Biomed & Clin Neurosci, Palermo, PA, Italy

[5] CNR, Palermo, PA, Italy

来源：

BIOGERONTOLOGY | 2011年 / 12卷 / 05期

关键词：

ABO; Centenarian; Genotyping; Immunogenetics; Longevity; SUSCEPTIBILITY; DISEASE; RISK;

D O I：

10.1007/s10522-011-9350-7

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing extended life expectancy, hence considering them as biomarkers of age-related diseases onset and development. The present study shows no significant differences between allelic variations of ABO blood groups among a group of centenarians from Western Sicily.

引用

页码：467 / 471

页数：5

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