Blood group does not appear to affect longevity a pilot study in centenarians from Western Sicily

被引：6
|
作者：
Vasto, Sonya [1 ,2 ,3 ]
Caruso, Calogero [2 ,3 ]
Castiglia, Laura [2 ,3 ]
Duro, Giovanni [5 ]
Monastero, Roberto [4 ]
Rizzo, Claudia [2 ,3 ]
机构：
[1] AOUP PAOLO GIACCONE, UO Immunoematol & Med Trasfus, I-90127 Palermo, PA, Italy
[2] Univ Med Sch Paolo Giaccone Hosp, Immunohaemathol Unit, Palermo, PA, Italy
[3] Univ Palermo, Dept Pathobiol Med & Forens Biotechnol, Palermo, PA, Italy
[4] Univ Palermo, Dept Expt Biomed & Clin Neurosci, Palermo, PA, Italy
[5] CNR, Palermo, PA, Italy
来源：
BIOGERONTOLOGY | 2011年 / 12卷 / 05期
关键词：
ABO; Centenarian; Genotyping; Immunogenetics; Longevity; SUSCEPTIBILITY; DISEASE; RISK;
D O I：
10.1007/s10522-011-9350-7
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing extended life expectancy, hence considering them as biomarkers of age-related diseases onset and development. The present study shows no significant differences between allelic variations of ABO blood groups among a group of centenarians from Western Sicily.
引用
收藏
页码：467 / 471
页数：5
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