Inhibitory synapses turn exciting

被引:0
|
作者
Kauer, JA [1 ]
机构
[1] Brown Univ, Dept Mol Pharmacol Physiol & Biotechnol, Providence, RI 02912 USA
关键词
D O I
10.1038/nn0305-257
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
How activity-dependent synaptic plasticity shapes the development of inhibitory synapses has remained unclear. In this issue, Gillespie et al. show that in the developing rat auditory system, inhibitory synapses transiently co-release glutamate. The consequent activation of postsynaptic NMDA receptors may be critical for the plasticity mechanisms that determine tonotopic sharpening.
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页码:257 / 258
页数:2
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