Two New Secoiridoid Glucosides from the Twigs of Cornus officinalis

被引：8
|
作者：
Li, Yong-chao [1 ]
Yang, Jing [1 ]
Li, Jun-ke [2 ]
Liang, Xin-hong [2 ]
Sun, Jun-liang [2 ]
机构：
[1] Henan Inst Sci & Technol, Life Sch Sci & Technol, Luoyang 453003, Henan, Peoples R China
[2] Henan Inst Sci & Technol, Sch Food Sci, Luoyang 453003, Henan, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2016年 / 52卷 / 04期
关键词：
Cornus officinalis; officinaloside A; antibacterial activity; CONSTITUENTS; GLYCOSIDE; TANNINS;
D O I：
10.1007/s10600-016-1730-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new compounds, officinaloside A (1) and 8R-hydroxy-10-hydrosweroside (2), together with a known one, 8S-hydroxy-10-hydrosweroside (3), were isolated from the twigs of Cornus officinalis. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analyses (HR-MS, 1D and 2D NMR). Compound 1 showed inhibition on the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus with minimum inhibition concentrations (MICs) of 25, 12.5, and 50 ug/mL, respectively.
引用
收藏
页码：647 / 650
页数：4
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