Two New Secoiridoid Glucosides from the Twigs of Cornus officinalis

被引：8

作者：

Li, Yong-chao ^{[1
]}

Yang, Jing ^{[1
]}

Li, Jun-ke ^{[2
]}

Liang, Xin-hong ^{[2
]}

Sun, Jun-liang ^{[2
]}

机构：

[1] Henan Inst Sci & Technol, Life Sch Sci & Technol, Luoyang 453003, Henan, Peoples R China

[2] Henan Inst Sci & Technol, Sch Food Sci, Luoyang 453003, Henan, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2016年 / 52卷 / 04期

关键词：

Cornus officinalis; officinaloside A; antibacterial activity; CONSTITUENTS; GLYCOSIDE; TANNINS;

D O I：

10.1007/s10600-016-1730-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new compounds, officinaloside A (1) and 8R-hydroxy-10-hydrosweroside (2), together with a known one, 8S-hydroxy-10-hydrosweroside (3), were isolated from the twigs of Cornus officinalis. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analyses (HR-MS, 1D and 2D NMR). Compound 1 showed inhibition on the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus with minimum inhibition concentrations (MICs) of 25, 12.5, and 50 ug/mL, respectively.

引用

页码：647 / 650

页数：4

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