Synthesis of pyrrole- and indole-containing nitropropanoates on the basis of β-heteryl-α-nitroacrylates

Synthetic approach to beta-furyl- and beta-thienyl-alpha-nitroacrylates was modified. It was established that these nitroethenes react with pyrrole, N-methylpyrrole, and substituted indole derivatives in the absence of catalyst to afford products of the alkylation of pyrrole C-2 and indole C-3 reaction sites. A possibility of this reaction to proceed under "dry reaction" condition on a silicagel surface was shown.